Patents by Inventor Melanie Proulx

Melanie Proulx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IAP BIR domain binding compounds
    Patent number: 9284350
    Abstract: A compound of Formula 1: (I) or salt thereof, as well as methods of making compounds of Formula 1, methods of using compounds of Formula 1 to treat proliferative disorders such as cancer, and related compounds, composition, and methods.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: March 15, 2016
    Assignee: Pharmascience Inc.
    Inventors: Alain Laurent, Melanie Proulx, Yannick Rose, Irina Denissova, Kenza Dairi, Scott Jarvis, James B. Jaquith
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 8829030
    Abstract: Compounds represented by formula: Wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: September 9, 2014
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thunkunta Jagadeeswar Reddy, Ming Qiang Zhang
  • IAP BIR DOMAIN BINDING COMPOUNDS
    Publication number: 20130040892
    Abstract: A compound of Formula 1: (I) or salt thereof, as well as methods of making compounds of Formula 1, methods of using compounds of Formula 1 to treat proliferative disorders such as cancer, and related compounds, composition, and methods.
    Type: Application
    Filed: February 11, 2011
    Publication date: February 14, 2013
    Applicant: PHARMASCIENCE INC.
    Inventors: Alain Laurent, Melanie Proulx, Yannick Rose, Irina Denissova, Kenza Dairi, Scott Jarvis, James B. Jaquith
  • Compounds and methods for the treatment or prevention of flavivirus infections
    Patent number: 8357718
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: January 22, 2013
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS
    Publication number: 20120009141
    Abstract: A compound of Formula 1: or a salt thereof, and methods for the use thereof, especially as an IAP inhibitor, as well as related compounds, compositions, and methods.
    Type: Application
    Filed: August 7, 2009
    Publication date: January 12, 2012
    Applicant: PHARMASCIENCE INC.
    Inventors: Alain Laurent, Melanie Proulx, James B. Jaquith, Irina Denissova
  • BRIDGED SECONDARY AMINES AND USE THEREOF AS IAP BIR DOMAIN BINDING COMPOUNDS
    Publication number: 20110171171
    Abstract: A compound of Formula 1.1A: 1.1A or salt thereof, as well as methods of making compounds of Formula 1.1A, methods of using compounds of Formula 1.1A to treat proliferative disorders such as cancer, and related compounds, composition, and methods.
    Type: Application
    Filed: June 26, 2009
    Publication date: July 14, 2011
    Applicant: Aegera Therapeutics, Inc.
    Inventors: Alain Laurent, Melanie Proulx, Yannick Rose, James B. Jaquith, Stephen Morris
  • FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS
    Publication number: 20110117081
    Abstract: A compound of Formula (1) or a salt thereof, methods for the preparation and use of such a compound, especially as an IAP inhibitor, and related compounds, compositions, and methods.
    Type: Application
    Filed: May 5, 2009
    Publication date: May 19, 2011
    Applicant: Aegera Therapeutics, Inc.
    Inventors: Alain Laurent, Melanie Proulx, James Jaquith
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 7402608
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: July 22, 2008
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Spirohydantoin compounds and methods for the modulation of chemokine receptor activity
    Patent number: 7351713
    Abstract: Compounds of formula I wherein R1, R2, R3, R4 and R5 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: April 1, 2008
    Assignee: Viro Chem Pharma, Inc.
    Inventors: Laval Chan Chun Kong, Ming-Qiang Zhang, Christophe Moinet, Marc Courchesne, Thumkunta Jagadeeswar Reddy, Melanie Proulx
  • Spiro compounds and methods for the modulation of chemokine receptor activity
    Publication number: 20050075326
    Abstract: Novel compounds represented by formula I: wherein Y, Z, X, W, R1, R2 and R3 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity and the treatment or prevention of diseases associated therewith.
    Type: Application
    Filed: July 19, 2004
    Publication date: April 7, 2005
    Inventors: Laval Chan Chun Kong, Ming Zhang, Christophe Moinet, Melanie Proulx, Thumkunta Reddy, Marc Courchesne
  • Spirohydantoin compounds and methods for the modulation of chemokine receptor activity
    Publication number: 20050075360
    Abstract: Compounds of formula I wherein R1, R2, R3, R4 and R5 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.
    Type: Application
    Filed: September 10, 2004
    Publication date: April 7, 2005
    Inventors: Laval Chan Chun Kong, Ming-Qiang Zhang, Christophe Moinet, Marc Courchesne, Thumkunta Reddy, Melanie Proulx
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20050009804
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Application
    Filed: December 9, 2003
    Publication date: January 13, 2005
    Inventors: Laval Chan Chun Kong, Sanjoy Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Pereira, Carl Poisson, Melanie Proulx, Thumkunta Reddy, Zhang Ming-Qiang