Abstract: Low-dose IL-2 has been proposed as a therapy to rectify regulatory T cell (Treg) fitness in type 1 diabetes (T1D). Identification of a combinatorial approach permits lower IL-2 dosing and avoids off-target effects. Insulin-like growth factor-1 (IGF1) is a hormone that promotes immunoregulation. Disclosed are methods that synergizes IGF1 with IL-2 to expand Tregs. In vivo IL-2+IGF1 treatment expands murine Tregs to a greater extent than either agent alone. IGF1+IL-2 treatment permits gene transfer in primary human Treg without the requirement for conventional activation stimuli, observing that IGF1+IL-2 maintains Treg naivety.

Abstract: Biometric recognition systems and methods are described, including a biometric recognition system including a user system with a biometric able to scan a finger and provide an image. From the image, a plurality of features may be extracted to create at least one fingerprint feature vector using a convolutional neural network.

Abstract: A biometric recognition system is described. The biometric recognition system includes a user system with a biometric able to scan a finger and provide an image. From the image, a plurality of features are extracted to create at least one fingerprint feature vector using a convolutional neural network.

Abstract: A wearable device having one or more processors configured to receive one or more signals representative of biometric parameter(s) and sensed presence of a user. The one or more processors configured to compare the biometric parameter to a stored user parameter for authentication of the user. Upon authentication, the one or more processors switch from a locked mode to an unlocked mode to enable communication.

Abstract: A wearable device having one or more processors configured to receive one or more signals representative of biometric parameter(s) and sensed presence of a user. The one or more processors configured to compare the biometric parameter to a stored user parameter for authentication of the user. Upon authentication, the one or more processors switch from a locked mode to an unlocked mode to enable communication.

Abstract: A wearable device having one or more processors configured to receive one or more signals representative of biometric parameter(s) and sensed presence of a user. The one or more processors configured to compare the biometric parameter to a stored user parameter for authentication of the user. Upon authentication, the one or more processors switch from a locked mode to an unlocked mode to enable communication.

Abstract: A wearable device having one or more processors configured to receive one or more signals representative of biometric parameter(s) and sensed presence of a user. The one or more processors configured to compare the biometric parameter to a stored user parameter for authentication of the user. Upon authentication, the one or more processors switch from a locked mode to an unlocked mode to enable communication.

Abstract: A wearable device having one or more processors configured to receive one or more signals representative of biometric parameter(s) and sensed presence of a user. The one or more processors configured to compare the biometric parameter to a stored user parameter for authentication of the user. Upon authentication, the one or more processors switch from a locked mode to an unlocked mode to enable communication.

Abstract: The present disclosure describes a method in which an encrypted request to transfer a requested amount of cryptocurrency from a user address to a destination address is received. The request includes a destination address, a requested amount, a user device encryption key, and biometric data. A partially signed transaction to transfer a requested amount of cryptocurrency from the user address to the destination address is also received. The partially signed transaction is cryptographically signed and a multi-signed transaction is broadcast to a cryptocurrency network to transfer the requested amount of cryptocurrency from the user address to the destination address.