Patents by Inventor Melanie Yorke-Smith

Melanie Yorke-Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell surface glycoprotein
    Patent number: 8124748
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: February 28, 2012
    Assignee: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • CSF3R polypeptides and uses thereof
    Patent number: 7871979
    Abstract: The present invention relates to CSF3R polypeptide variants and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinant cells containing the same. The invention further discloses methods of producing such polypeptides, as well as methods and tools for detecting or dosing these polypeptides in any sample.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: January 18, 2011
    Assignee: Merck Serono SA
    Inventors: Melanie Yorke-Smith, Andreas Pigni
  • TREATMENT AND/OR PREVENTION OF CANCER AND/OR ARTHRITIS
    Publication number: 20100303760
    Abstract: The invention relates to the use of INSP163 for treatment and/or prevention of cancer and/or musculoskeletal/connective tissue disorder, in particular of lung cancer and/or osteoarthritis. Combinations of INSP163 with an interferon, a TNF antagonist or a further anti-cancer or anti-arthritis agent are also within the present invention.
    Type: Application
    Filed: April 20, 2006
    Publication date: December 2, 2010
    Applicant: Laboratoires Serono SA
    Inventors: Christine Power, Melanie Yorke-Smith
  • REELER DOMAIN CONTAINING PROTEIN
    Publication number: 20100196349
    Abstract: This invention relates to protein INSP 171, herein identified as containing a Reeler domain, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: December 4, 2006
    Publication date: August 5, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Christine Power, Melanie Yorke-Smith, Richard Fagan, Tania Rodrigues, Dave Michalovich
  • CSF3R POLYPEPTIDES AND USES THEREOF
    Publication number: 20100004167
    Abstract: The present invention relates to CSF3R polypeptide variants and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinant cells containing the same. The invention further discloses methods of producing such polypeptides, as well as methods and tools for detecting or dosing these polypeptides in any sample.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 7, 2010
    Applicant: Laboratoires Serono SA
    Inventors: Melanie Yorke-Smith, Andreas Pigni
  • TREATMENT AND/OR PREVENTION OF CANCER AND/OR ARTHRITIS
    Publication number: 20090035274
    Abstract: The invention relates to the use of INSP163 for treatment and/or prevention of cancer and/or musculoskeletal/connective tissue disorder, in particular of lung cancer and/or osteoarthritis. Combinations of INSP163 with an interferon, a TNF antagonist or a further anti-cancer or anti-arthritis agent are also within the present invention.
    Type: Application
    Filed: April 20, 2006
    Publication date: February 5, 2009
    Applicant: Laboratoires Serono SA
    Inventors: Christine Power, Melanie Yorke-Smith
  • Lipocalin Protein
    Publication number: 20080254035
    Abstract: The invention is based on the discovery that the human protein referred to herein as INSP181 protein is a lipocalin.
    Type: Application
    Filed: March 8, 2006
    Publication date: October 16, 2008
    Applicant: Ares Trading S.A.
    Inventors: Melanie Yorke-Smith, Christine Power, Ursula Boschert
  • Cell Surface Glycoprotein
    Publication number: 20080124309
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: August 11, 2005
    Publication date: May 29, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • Splice Variant of Unc5h2
    Publication number: 20080038255
    Abstract: The present invention provides an UNC5H2 splice variant polypeptide, UNC5H2d, and the nucleic acid molecule encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing the UNC5H2d polypeptide. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with the UNC5H2d polypeptide.
    Type: Application
    Filed: June 3, 2005
    Publication date: February 14, 2008
    Applicant: Aplied Research Systems ARS Holding N.V.
    Inventors: Christine Power, Melanie Yorke-Smith
  • Leucine rich repeat containing protein
    Publication number: 20070148655
    Abstract: This invention relates to the novel protein, termed INSP (179), herein identified as a secreted protein, in particular as a member of the leucine rich repeat containing protein family and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: February 14, 2005
    Publication date: June 28, 2007
    Applicant: Ares Trading S.A.
    Inventors: David Michalovich, Simon White, Christine Power, Melanie Yorke-Smith