Abstract: The present invention refers to a medical apparatus that allows to generate, non-invasively and at a requested depth shear waves of controlled frequency and amplitude. The purpose is to impact via mechanotransduction on cellular behavior, i.e. cell proliferation and cell migration. The aim is to aide classical tumor therapy for instance by rendering cells more receptive to drugs, or by gaining time during chemotherapy by reducing cell migration and hence slowing down the metastatic process.

Abstract: The invention relates to a method or operating mode which, using a device for emitting and receiving sonic and/or ultrasonic torsional waves, can be used to obtain data relating to the consistency or elasticity of quasi-incompressible solid media, preferably quasi-fluids or biological tissues, based on the separation of non-linear parameters.

Abstract: A panel element for use as a roof tile or other building element, e.g. on a vertical surface, is molded in one piece and includes upper, lower and left and right marginal edge regions. To facilitate securing the panel in place, the upper edge region may include fastening apertures. The lower marginal edge region of each panel is secured to the upper edge region of another panel in a lower row of panels. For this purpose, interlocking formations are provided in the upper and lower marginal edge regions, with the locking formation in the upper marginal edge region being below the nail apertures. This locking formation can serve both to prevent water travelling up to the nail apertures and as a locking formation. Support ribs under the panels can provide both uniform support from an underlying planar surface, and can also form the locking formations. The panel can be molded in any suitable material to simulate a variety of known tiles or other building elements.