Patents by Inventor Melinda M. Hutton

Melinda M. Hutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Inducing a TRIF-Bias
    Publication number: 20170072050
    Abstract: Compositions comprising a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF-biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527.
    Type: Application
    Filed: April 20, 2016
    Publication date: March 16, 2017
    Inventors: William S. BOWEN, Jay T. EVANS, Melinda M. HUTTON, David A. JOHNSON, Laurie A. MINNS
  • Method for Inducing a TRIF-Bias
    Publication number: 20150004180
    Abstract: Compositions comprising a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF-biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527.
    Type: Application
    Filed: December 23, 2013
    Publication date: January 1, 2015
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: WILLIAM S. BOWEN, Jay T. EVANS, MELINDA M. HUTTON, DAVID A. JOHNSON, LAURIE A. MINNS
  • Method for inducing a TRIF-bias
    Patent number: 8629116
    Abstract: The use of a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: January 14, 2014
    Assignee: GlaxoSmithKline Biologicals S.A.
    Inventors: William S. Bowen, Jay T. Evans, Melinda M. Hutton, David A. Johnson, Laurie A. Minns
  • Method for Inducing a Trif-Bias
    Publication number: 20110257113
    Abstract: The use of a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527.
    Type: Application
    Filed: December 23, 2009
    Publication date: October 20, 2011
    Inventors: William S. Bowen, Jay T. Evans, Melinda M. Hutton, David A. Johnson, Laurie A. Minns