Patents by Inventor Melissa A. KACHURA

Melissa A. KACHURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
    Patent number: 11981670
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Grant
    Filed: August 16, 2021
    Date of Patent: May 14, 2024
    Assignee: Dynavax Technologies Corporation
    Inventors: Stewart D. Chipman, Radwan Kiwan, Melissa A. Kachura, Robert Coffman
  • ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE TLR7/8 AGONIST COMPOUNDS AND USES THEREOF
    Publication number: 20220033400
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Application
    Filed: August 16, 2021
    Publication date: February 3, 2022
    Applicant: Dynavax Technologies Corporation
    Inventors: Stewart D. CHIPMAN, Radwan KIWAN, Melissa A. KACHURA, Robert COFFMAN
  • Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
    Patent number: 11124510
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: September 21, 2021
    Assignee: DYNAVAX TECHNOLOGIES CORPORATION
    Inventors: Stewart D. Chipman, Radwan Kiwan, Melissa A. Kachura, Robert Coffman
  • ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE TLR7/8 AGONIST COMPOUNDS AND USES THEREOF
    Publication number: 20200199124
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicant: Dynavax Technologies Corporation
    Inventors: Stewart D. CHIPMAN, John DEMATTEI, Radwan KIWAN, Melissa A. KACHURA
  • Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof
    Patent number: 10618896
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: April 14, 2020
    Assignee: Dynavax Technologies Corporation
    Inventors: Stewart D. Chipman, John Demattei, Radwan Kiwan, Melissa A. Kachura
  • ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE TLR7/8 AGONIST COMPOUNDS AND USES THEREOF
    Publication number: 20190062329
    Abstract: Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 28, 2019
    Applicant: Dynavax Technologies Corporation
    Inventors: Stewart D. CHIPMAN, John DEMATTEI, Radwan KIWAN, Melissa A. KACHURA