Patents by Inventor Melissa Herbst-Kralovetz

Melissa Herbst-Kralovetz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mucosal immunization
    Patent number: 9585954
    Abstract: A method for eliciting an immune response by contacting a mucosal surface utilizing a composition including an antigen, a NOD agonist, and a mucoadhesive, wherein the NOD agonist is N-Acetyl-muramyl-L-Alanyl-D-Glutamin-n-butyl-ester (“Murabutide”).
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: March 7, 2017
    Assignee: ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Melissa Herbst-Kralovetz, Charles J. Arntzen, Daniel Tusé
  • Stabilized virus like particles having enhanced mucosal immunogenicity
    Patent number: 9439958
    Abstract: A method of producing an immune response in a subject including the step of administering to the subject a dry powder vaccine composition having a dry powder containing a subunit antigen with virus-like particles, where the subunit antigen is stabilized by a polysaccharide-containing plant extract, and where mucosal vaccination results in an immune response which is not further enhanced by co-inclusion of adjuvants.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: September 13, 2016
    Assignee: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Charles J. Arntzen, Melissa Herbst-Kralovetz
  • Mucosal Immunization
    Publication number: 20140065185
    Abstract: A method for eliciting an immune response by contacting a mucosal surface utilizing a composition including an antigen, a NOD agonist, and a mucoadhesive, wherein the NOD agonist is N-Acetyl-muramyl-L-Alanyl-D-Glutamin-n-butyl-ester (“Murabutide”).
    Type: Application
    Filed: October 31, 2013
    Publication date: March 6, 2014
    Applicant: ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Melissa Herbst-Kralovetz, Charles J. Arntzen, Daniel Tusé
  • STABILIZED VIRUS LIKE PARTICLES HAVING ENHANCED MUCOSAL IMMUNOGENICITY
    Publication number: 20130095134
    Abstract: This disclosure relates to compositions and methods for inducing immune response. Specifically, the disclosure relates to a composition comprising a subunit antigen stabilized by a polysaccharide-containing plant extract, in which the antigen consists of virus-like particles that have enhanced mucosal immuno-genicity as a result of the stabilization.
    Type: Application
    Filed: December 23, 2010
    Publication date: April 18, 2013
    Applicant: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Charles J. Arntzen, Melissa Herbst-Kralovetz
  • Mucosal Immunization
    Publication number: 20120121710
    Abstract: Methods and compositions for eliciting an immune response to an antigen are disclosed. In certain aspects, these methods concern eliciting an immune response in a subject by administering to the mucosa of the subject a composition comprising a virus-like particle (“VLP”) and Murabutide.
    Type: Application
    Filed: March 26, 2010
    Publication date: May 17, 2012
    Applicant: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Melissa Herbst-Kralovetz, Charles J. Arntzen, Daniel Tusé