Patents by Inventor Melissa J. Birch

Melissa J. Birch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORM OF LORLATINIB FREE BASE
    Publication number: 20190365712
    Abstract: This invention relates to acrystalline form of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h] [2,5,11]benzoxadiazacyclo-tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.
    Type: Application
    Filed: August 8, 2019
    Publication date: December 5, 2019
    Applicant: Pfizer Inc.
    Inventors: Klimentina Dimitrova Pencheva, Melissa J. Birch, Mark McAllister, Martin Rowland, Ian Leonard Smales
  • Crystalline form of lorlatinib free base
    Patent number: 10420749
    Abstract: This invention relates to a crystalline form of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h] [2,5,11]benzoxadiazacyclo-tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: September 24, 2019
    Assignee: Pfizer Inc.
    Inventors: Klimentina Dimitrova Pencheva, Melissa J. Birch
  • CRYSTALLINE FORM OF LORLATINIB FREE BASE
    Publication number: 20180235933
    Abstract: This invention relates to acrystalline form of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h] [2,5,11]benzoxadiazacyclo-tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 23, 2018
    Applicant: Pfizer Inc.
    Inventors: Klimentina Dimitrova Pencheva, Melissa J. Birch