Abstract: Embodiments include devices and methods that enable loading of a fluid sample by capillary action and provide for subsequent thinning of the fluid layer for imaging of a processed sample. A device includes a substrate, a transparent cover, and one or more pillars separating the transparent cover from the substrate where the height of the one or more pillars sets a spacing between the transparent cover and the substrate prior to introduction of a fluid sample to the device. The one or more pillars may be soluble in aqueous fluids and/or soluble in a component of the fluid sample. The spacing between the substrate and the transparent cover may be configured to draw the fluid sample into a space between the substrate and the transparent cover via capillary forces.

Abstract: A non-invasive, calorimetric infection detector is provided, comprised of a substrate, and one or more indicator compositions disposed upon or incorporated therein. These indicator compositions exhibit a persistent change color when exposed to gaseous oxides of nitrogen and acids formed therefrom, providing a means of detecting NO production in a wound, which has been found to occur at a high level at the onset of infection in a wound. In addition, a bandage is provided, comprised of the detector, as well as a porous portion, and preferably a hydrophobic barrier layer to protect the detector from contamination by water and other fluids draining from the wound. The non-invasive, calorimetric infection detector, and bandage containing same, can be utilized to provide a convenient, easily utilized colorimetric means of detecting the onset of wound infection, thereby enabling caregivers to effectively and timely treat infections.

Abstract: Disclosed and claimed herein is an electrode stack having a first electrode, an electrolyte comprising a REDOX couple, a conductive layer disposed on a substrate, wherein the conductive layer is a flaked conductor, and a binder and wherein the conductor is chosen to resist corrosion in the presence of the electrolyte.

Abstract: A non-invasive, calorimetric infection detector is provided, comprised of a substrate, and one or more indicator compositions disposed upon or incorporated therein. These indicator compositions exhibit a persistent change color when exposed to gaseous oxides of nitrogen and acids formed therefrom, providing a means of detecting NO production in a wound, which has been found to occur at a high level at the onset of infection in a wound. In addition, a bandage is provided, comprised of the detector, as well as a porous portion, and preferably a hydrophobic barrier layer to protect the detector from contamination by water and other fluids draining from the wound. The non-invasive, calorimetric infection detector, and bandage containing same, can be utilized to provide a convenient, easily utilized colorimetric means of detecting the onset of wound infection, thereby enabling caregivers to effectively and timely treat infections.