Patents by Inventor Melissa S. Hasenbank

Melissa S. Hasenbank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface
    Patent number: 7659089
    Abstract: The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a conductive surface and contacting a substrate capable of producing a detectable signal upon oxidation or reduction with a second region of the conductive surface. The second region is electrically coupled with the first region and the redox enzyme is not present in the second region. The method further comprises exposing the immobilized redox enzyme to conditions that effect oxidation or reduction of the enzyme, and detecting oxidation or reduction of the substrate at the second region. The invention can be adapted for detecting a plurality of analytes.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: February 9, 2010
    Assignee: University of Washington
    Inventors: Melissa S. Hasenbank, Elain S. Fu, Paul Yager
  • Chemical Sensor Enhanced by Direct Coupling of Redox Enzyme to Conductive Surface
    Publication number: 20080153121
    Abstract: The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a conductive surface and contacting a substrate capable of producing a detectable signal upon oxidation or reduction with a second region of the conductive surface. The second region is electrically coupled with the first region and the redox enzyme is not present in the second region. The method further comprises exposing the immobilized redox enzyme to conditions that effect oxidation or reduction of the enzyme, and detecting oxidation or reduction of the substrate at the second region. The invention can be adapted for detecting a plurality of analytes.
    Type: Application
    Filed: March 11, 2008
    Publication date: June 26, 2008
    Applicant: University of Washington
    Inventors: Melissa S. Hasenbank, Elain S. Fu, Paul Yager
  • Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface
    Patent number: 7364886
    Abstract: The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a conductive surface and contacting a substrate capable of producing a detectable signal upon oxidation or reduction with a second region of the conductive surface. The second region is electrically coupled with the first region and the redox enzyme is not present in the second region. The method further comprises exposing the immobilized redox enzyme to conditions that effect oxidation or reduction of the enzyme, and detecting oxidation or reduction of the substrate at the second region. The invention can be adapted for detecting a plurality of analytes.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: April 29, 2008
    Assignee: University of Washington
    Inventors: Melissa S. Hasenbank, Elain S. Fu, Paul Yager