Abstract: Described herein are methods of determining segregation dynamics of mitochondrial DNA herein. Also described herein are methods of diagnosing, prognosing, and/or monitoring a mitochondrial disease.

Abstract: A system and method are disclosed for locating, collecting, collating, analyzing, and reporting on summarized data that is generated from regulatory compliance matter data. Data is collected and compiled from multiple sources, including government databases, web pages, and regulatory documents; These collected data are consolidated and reconciled. A single topic record is created for a person, company, or product. Duplication and redundancy within the information are reduced. Corrections in data format are made for inconsistencies that exist between different information sources. Broad and/or narrow searches are enabled with the retrieval of information and/or relevant documents. The integrated data and associated analyses can be presented in reports that can be made accessible through a LAN, a WAN, a desktop, and/or a web interface.