Abstract: An example fluid collection assembly includes a fluid impermeable barrier defining at least one opening, a chamber in fluid communication with the at least one opening, and at least one fluid outlet. The fluid collection assembly also includes at least one porous material (e.g., at least one wicking material) disposed in the chamber. The fluid collection assembly also includes at least one conduit attached to the fluid outlet. Further, the fluid collection assembly includes one or more leak prevention features.

Abstract: Embodiments relate to devices, systems, and methods for collecting fluid, such as bodily fluid. An example fluid collection system may include a fluid collection device for collecting fluid from a subject and a fluid collection pad. The fluid collection pad may include a cushion, a fluid collection container having an absorbent portion disposed therein. The fluid collection container may be disposed within the cushion and a tube having a first portion configured to couple to the fluid collection device and a second portion may be disposed within the fluid collection container. The second portion of the tube may be perforated.

Abstract: Embodiments relate to devices, systems, and methods for collecting fluid, such as bodily fluid. An example fluid collection system may include a fluid collection device for collecting fluid from a subject and a fluid collection pad. The fluid collection pad may include a cushion, a fluid collection container having an absorbent portion disposed therein. The fluid collection container may be disposed within the cushion and a tube having a first portion configured to couple to the fluid collection device and a second portion may be disposed within the fluid collection container. The second portion of the tube may be perforated.

Abstract: A portable urine collection system (200) may include a urine collection device, a conduit (217) in fluid communication with the urine collection device (212), a urine collection container (214) having an interior region, a pump (216), and a container support (202). The pump is in fluid communication with the urine collection container and is configured to pull a vacuum on the interior region of the urine collection container effective to draw urine from the urine collection device through the conduit into the urine collection container. The container support is configured to detachably secure to a wheelchair and support at least the urine collection container.

Abstract: A portable urine collection system (10) may include a urine collection device (12), a first conduit (17) in fluid communication with the urine collection device, a urine collection container (14) having an interior region, a pump (16), a sensor (215), and a cover. The pump is in fluid communication with the urine collection container and is configured to pull a vacuum on the interior region of the urine collection container effective to draw urine from the urine collection device through the first conduit into the urine collection container. The sensor is secured to the container and is configured to detect a property relating at least to a volume of the urine in the urine collection container. The cover is sized and dimensioned to hold at least the pump therein and obscure at least the pump from view outside the cover.

Abstract: A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the

Abstract: Examples relate to devices, systems, and methods for fluid collection such as urine. The urine collection device includes a fluid impermeable barrier and a fluid permeable body. The fluid impermeable barrier at least partially defines a chamber. The fluid impermeable barrier includes at least one elongated portion having a first width and distal to the aperture and a second portion having a second width greater than the first width. The second portion at least partially defines an opening in the fluid impermeable barrier, and the opening has a maximum lateral dimension greater than the first width of the elongated portion. The fluid permeable body is configured to wick fluid away from the opening into the at least one elongated portion.

Abstract: An example fluid collection assembly includes a fluid impermeable barrier defining at least one opening, a chamber in fluid communication with the at least one opening, and at least one fluid outlet. The fluid collection assembly also includes at least one porous material (e.g., at least one wicking material) disposed in the chamber. The fluid collection assembly also includes at least one conduit attached to the fluid outlet. Further, the fluid collection assembly includes one or more leak prevention features.

Abstract: A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the

Abstract: A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the

Abstract: It has been established that cancer cells with oncogenic mutants in the small GTPase K-Ras are susceptible to antibodies that bind intracellular guanosine, but delivery of antibodies into cells can be challenging. A subset of lupus autoantibodies is associated with anti-guanosine activity, and is capable of cellular penetration. These antibodies have potential as therapeutic agents targeted towards K-Ras associated malignancies.

Abstract: It has been established that cancer cells with oncogenic mutants in the small GTPase K-Ras are susceptible to antibodies that bind intracellular guanosine, but delivery of antibodies into cells can be challenging. A subset of lupus autoantibodies is associated with anti-guanosine activity, and is capable of cellular penetration. These antibodies have potential as therapeutic agents targeted towards K-Ras associated malignancies.

Abstract: A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the

Abstract: A method of forming a leaflet of a prosthetic valve includes placing a first piece of material on a working surface. A leaflet mold is placed on the first piece of material, and provides a outer peripheral shape comprising a curved portion. A second piece of material is placed over the first piece and the leaflet mold. The first and second pieces of material are stitched to one another along at least a portion of the curved portion of the leaflet mold. The leaflet mold is removed from first and second pieces of material.

Abstract: A method of forming a leaflet of a prosthetic valve includes placing a first piece of material on a working surface. A leaflet mold is placed on the first piece of material, and provides a outer peripheral shape comprising a curved portion. A second piece of material is placed over the first piece and the leaflet mold. The first and second pieces of material are stitched to one another along at least a portion of the curved portion of the leaflet mold. The leaflet mold is removed from first and second pieces of material.

Abstract: A mold assembly for forming a prosthetic valve having at least one leaflet, which includes a first plate having a first side from which at least one leaflet mold extends and a planar portion adjacent the at least one leaflet mold, wherein the planar portion has multiple access holes through its thickness, and a second plate having at least one mold opening and a planar portion adjacent the at least one mold opening, wherein each mold opening is sized and shaped to correspond with one of the leaflet molds of the first plate, and wherein the planar portion has multiple access holes through its thickness. The second plate is positionable relative to the first plate so that each of the leaflet molds of the first plate extend at least partially through one of the mold openings of the second plate.

Abstract: A mold assembly for forming a prosthetic valve having at least one leaflet, which includes a first plate having a first side from which at least one leaflet mold extends and a planar portion adjacent the at least one leaflet mold, wherein the planar portion has multiple access holes through its thickness, and a second plate having at least one mold opening and a planar portion adjacent the at least one mold opening, wherein each mold opening is sized and shaped to correspond with one of the leaflet molds of the first plate, and wherein the planar portion has multiple access holes through its thickness. The second plate is positionable relative to the first plate so that each of the leaflet molds of the first plate extend at least partially through one of the mold openings of the second plate.