Patents by Inventor Melita Irving

Melita Irving has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210113615
    Abstract: The invention relates to heterodimeric inactivatable chimeric antigen receptors (CARs) and their use for treatment.
    Type: Application
    Filed: April 12, 2019
    Publication date: April 22, 2021
    Applicants: Ludwig Institute for Cancer Research Ltd., École Polytechnique Fédérale de Lausanne
    Inventors: George COUKOS, Melita IRVING, Bruno CORREIA, Pablo GAINZA-CIRAUQUI, Greta Maria Paola GIORDANO ATTIANESE
  • Publication number: 20200101110
    Abstract: The present invention relates to methods of designing kinase mutants for reprogramming the sensitivity of a target kinase to some specific inhibitors, methods of reprogramming the sensitivity of a target kinase to some specific inhibitors, wherein those kinase inhibitors have little or no affinity for the wild-type target kinase, vectors or cells expressing said mutated kinases, composition and uses thereof for the prevention and/or treatment of a disease or disorder, in particular cancer.
    Type: Application
    Filed: May 24, 2018
    Publication date: April 2, 2020
    Inventors: Olivier Michielin, Vincent Zoete, George Coukos, Melita Irving, Nahzli Dilek, Patrick Reichenbach, Kelly Ascencao