Patents by Inventor Melvin S. Oka

Melvin S. Oka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs
    Publication number: 20120115205
    Abstract: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.
    Type: Application
    Filed: August 30, 2010
    Publication date: May 10, 2012
    Applicant: ALLERGAN, INC.
    Inventors: LANCE E. STEWARD, MELVIN S. OKA
  • Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs
    Publication number: 20110111479
    Abstract: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.
    Type: Application
    Filed: August 30, 2010
    Publication date: May 12, 2011
    Applicant: ALLERGAN, INC.
    Inventors: LANCE E. STEWARD, MELVIN S. OKA
  • Botulinum neurotoxin serotype B activatable Botulinum neurotoxin serotype Bs
    Patent number: 7815917
    Abstract: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: October 19, 2010
    Assignee: Allergan, Inc.
    Inventors: Lance E. Steward, Melvin S. Oka
  • Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs
    Publication number: 20100075396
    Abstract: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.
    Type: Application
    Filed: May 1, 2009
    Publication date: March 25, 2010
    Applicant: ALLERGAN, INC.
    Inventors: Lance E. Steward, Melvin S. Oka
  • Clostridial toxin activatable Clostridial toxins
    Patent number: 7556817
    Abstract: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: July 7, 2009
    Assignee: Allergan, Inc.
    Inventors: Lance E. Steward, Melvin S. Oka