Patents by Inventor Melvin Yamamoto

Melvin Yamamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAPSULE CONTAINMENT OF DRIED REAGENTS
    Publication number: 20220032306
    Abstract: Disclosed herein are methods and devices for preparing a dried reagent for long term storage and rehydrating and mixing the dried reagent.
    Type: Application
    Filed: October 12, 2021
    Publication date: February 3, 2022
    Inventors: Thomas H. CAULEY III, Melvin YAMAMOTO
  • Methods and devices for reading microarrays
    Patent number: 10977478
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: April 13, 2021
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • CAPSULE CONTAINMENT OF DRIED REAGENTS
    Publication number: 20210008559
    Abstract: Disclosed herein are methods and devices for preparing a dried reagent for long term storage and rehydrating and mixing the dried reagent.
    Type: Application
    Filed: December 8, 2017
    Publication date: January 14, 2021
    Inventors: Thomas H. CAULEY, III, Melvin YAMAMOTO
  • METHODS AND DEVICES FOR READING MICROARRAYS
    Publication number: 20200265213
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: January 21, 2020
    Publication date: August 20, 2020
    Applicant: Affymetrix, inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Methods and devices for reading microarrays
    Patent number: 10586095
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: March 10, 2020
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • METHODS AND DEVICES FOR READING MICROARRAYS
    Publication number: 20190311178
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: April 3, 2019
    Publication date: October 10, 2019
    Applicant: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Methods and devices for reading microarrays
    Patent number: 10303922
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: May 28, 2019
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • METHODS AND DEVICES FOR READING MICROARRAYS
    Publication number: 20180341802
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: May 30, 2018
    Publication date: November 29, 2018
    Applicant: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Methods and devices for reading microarrays
    Patent number: 10019620
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: July 10, 2018
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • METHODS AND DEVICES FOR READING MICROARRAYS
    Publication number: 20180096190
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: August 25, 2017
    Publication date: April 5, 2018
    Applicant: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Methods and devices for reading microarrays
    Patent number: 9767342
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: September 19, 2017
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Automated method of manufacturing polyer arrays
    Patent number: 8652774
    Abstract: The present invention provides methods to process multiple sensors by providing a sensor plate and HT plates. In a preferred embodiment of the invention, methods for assembling microarray pegs and microarray plates are described for high throughput microarray processing.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: February 18, 2014
    Assignee: Affymetrix, Inc.
    Inventors: Melvin Yamamoto, Clifford A. Oostman, Jr., John S. Sze, Keith S. Pearson, Philip C. Trenholme, Dan Liu, Chi Sou Yu
  • System for photolithographic synthesis of polymer arrays
    Patent number: 8637434
    Abstract: The present invention provides novel processes for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. The methods of the invention combine high throughput process steps with high resolution photolithographic techniques in the manufacture of polymer arrays.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: January 28, 2014
    Assignee: Affymetrix, Inc.
    Inventors: Martin J. Goldberg, Martin Diggelman, Earl A. Hubbell, Glenn H. McGall, Ngo Nam, MacDonald S. Morris, Melvin Yamamoto, Jennifer Tan, Richard Rava
  • System and method for multiplex liquid handling
    Publication number: 20120329681
    Abstract: The present invention generally relates to microfabricated devices for carrying out and controlling chemical reactions and analysis. In particular, the present invention provides systems, methods, devices and computer software products related to multiplex liquid handling systems utilizing lab cards related to biological assays.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 27, 2012
    Applicant: AFFYMETRIX, INC.
    Inventors: Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings
    Patent number: 8309496
    Abstract: The present invention provides novel processes for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. The methods of the invention combine high throughput process steps with high resolution photolithographic techniques in the manufacture of polymer arrays.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: November 13, 2012
    Assignee: Affymetrix, Inc.
    Inventors: Martin J. Goldberg, Martin Diggelman, Earl A. Hubbell, Glenn H. McGall, Nam Quoc Ngo, MacDonald Morris, Melvin Yamamoto, Jennifer Tan, Richard P. Rava
  • Substrate preparation process
    Patent number: 8067578
    Abstract: The present invention provides novel processes for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. The methods of the invention combine high throughput process steps with high resolution photolithographic techniques in the manufacture of polymer arrays.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: November 29, 2011
    Assignee: Affymetrix, Inc.
    Inventors: Martin J Goldberg, Martin Diggelman, Earl A. Hubbell, Glenn H. McGall, Nam Quoc Ngo, MacDonald Morris, Melvin Yamamoto, Jennifer Tan, Richard P. Rava
  • System and Method for Making Lab Card by Embossing
    Publication number: 20110268832
    Abstract: In one aspect of the invention, systems, methods, and devices are provided for creating microfluidic and nanofluidic structures. In some embodiments, such systems, methods, and devices are used to create features with high aspect ratios in lab cards.
    Type: Application
    Filed: July 6, 2011
    Publication date: November 3, 2011
    Applicant: Affymetrix, INC.
    Inventors: Chuan Gao, Melvin Yamamoto
  • System and method for making lab card by embossing
    Patent number: 8007267
    Abstract: In one aspect of the invention, systems, methods, and devices are provided for creating microfluidic and nanofluidic structures. In some embodiments, such systems, methods, and devices are used to create features with high aspect ratios in lab cards.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: August 30, 2011
    Assignee: Affymetrix, Inc.
    Inventors: Chuan Gao, Melvin Yamamoto
  • METHODS AND DEVICES FOR READING MICROARRAYS
    Publication number: 20100296727
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: May 14, 2010
    Publication date: November 25, 2010
    Applicant: Affymetrix, INC.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • System and method for multiplex liquid handling
    Publication number: 20080311585
    Abstract: The present invention generally relates to microfabricated devices for carrying out and controlling chemical reactions and analysis. In particular, the present invention provides systems, methods, devices and computer software products related to multiplex liquid handling systems utilizing lab cards related to biological assays.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 18, 2008
    Applicant: Affymetrix, INC.
    Inventors: Chuan Gao, Melvin Yamamoto, Devin Nguyen