Patents by Inventor Melyssa BRATTON

Melyssa BRATTON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • S6K1 protein kinase inhibitors as cancer therapeutics
    Patent number: 12258315
    Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, especially RPS6K1 and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer, prostate cancer, lung cancer, and metastatic cancer.
    Type: Grant
    Filed: December 15, 2023
    Date of Patent: March 25, 2025
    Assignee: Xavier University of Louisiana
    Inventors: Jayalakshmi Sridhar, Melyssa Bratton, Rajesh Komati
  • S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS
    Publication number: 20240158351
    Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, especially RPS6K1 and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer, prostate cancer, lung cancer, and metastatic cancer.
    Type: Application
    Filed: December 15, 2023
    Publication date: May 16, 2024
    Inventors: Jayalakshmi SRIDHAR, Melyssa BRATTON, Rajesh KOMATI
  • S6K1 protein kinase inhibitors as cancer therapeutics
    Patent number: 11912660
    Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, especially RPS6K1 and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer, prostate cancer, lung cancer, and metastatic cancer.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: February 27, 2024
    Assignee: Xavier University of Louisiana
    Inventors: Jayalakshmi Sridhar, Melyssa Bratton, Rajesh Komati
  • PROTEIN KINASE INHIBITORS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20220378721
    Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, especially CK1? and/or CK1? inhibitors, which can be used to treat a serine threonine kinase-dependent disease and condition, such as neurodegenerative diseases like Alzheimer's Disease, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for neurodegenerative diseases, including Alzheimer's disease.
    Type: Application
    Filed: October 22, 2020
    Publication date: December 1, 2022
    Inventors: Jayalakshmi SRIDHAR, Melyssa BRATTON, Navneet GOYAL, Vishwajeet JHA, Richard SCHROEDER
  • S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS
    Publication number: 20210323919
    Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, especially RPS6K1 and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer, prostate cancer, lung cancer, and metastatic cancer.
    Type: Application
    Filed: April 16, 2021
    Publication date: October 21, 2021
    Inventors: Jayalakshmi SRIDHAR, Melyssa BRATTON, Rajesh KOMATI