Patents by Inventor Menashe Bar-Eli

Menashe Bar-Eli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic targeting of interleukins using siRNA in neutral liposomes
    Patent number: 8067390
    Abstract: The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: November 29, 2011
    Assignee: The Board of Regents of the University of Texas System
    Inventors: William M. Merritt, Anil K. Sood, Menashe Bar-Eli, Gabriel Lopez-Berestein
  • THERAPEUTIC TARGETING OF INTERLEUKINS USING SIRNA IN NEUTRAL LIPOSOMES
    Publication number: 20100172962
    Abstract: The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
    Type: Application
    Filed: February 29, 2008
    Publication date: July 8, 2010
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: William M. Merritt, Anil K. Sood, Menashe Bar-Eli, Gabriel Lopez-Berestein
  • Use of antibodies against the MUC18 antigen
    Publication number: 20060246077
    Abstract: The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.
    Type: Application
    Filed: June 30, 2006
    Publication date: November 2, 2006
    Inventors: Menashe Bar-Eli, Larry Green
  • Use of antibodies against the MUC18 antigen
    Patent number: 7090844
    Abstract: The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: August 15, 2006
    Assignee: Abgenix, Inc.
    Inventors: Menashe Bar-Eli, Larry L. Green
  • Methods for using anti-MUC18 antibodies
    Patent number: 7067131
    Abstract: The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: June 27, 2006
    Assignee: Abgenix, Inc.
    Inventors: Jean Gudas, Larry L. Green, Menashe Bar-Eli
  • Antibodies against the MUC18 antigen
    Patent number: 6924360
    Abstract: The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: August 2, 2005
    Assignee: Abgenix, Inc.
    Inventors: Larry L. Green, Menashe Bar-Eli
  • Use of antibodies against the MUC18 antigen
    Publication number: 20040115205
    Abstract: The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.
    Type: Application
    Filed: September 10, 2003
    Publication date: June 17, 2004
    Inventors: Menashe Bar-Eli, Larry L. Green
  • Methods for inhibition of angiogenesis, tumor growth and metastasis by fully human anti-IL8 and anti-MUC18 in diverse types of tumors
    Publication number: 20030068319
    Abstract: The present invention relates to methods of inhibiting hyperproliferative diseases. More specifically, it concerns treating a subject suffering from a hyperproliferative disease by administering an effective amount of a human anti-IL8 antibody composition and/or a human anti-MUC18 antibody composition such that the composition inhibits the disease.
    Type: Application
    Filed: March 22, 2002
    Publication date: April 10, 2003
    Inventor: Menashe Bar-Eli