Abstract: Disclosed herein is a submersible having one or more sensors configured to collect a signal from an interior area of a liquid carrying channel, and a processor configured to obtain the signal from the one or more sensors, calculate a diameter and a circumference of the liquid carrying channel according to the signal. determine whether an irregularity is present on an inner surface of the liquid carrying channel according to the diameter and the circumference, and generate a notification to notify an irregularity has been detected on the inner surface.

Abstract: Provided is a system and method for determination of a medical condition, the system including a disposable cartridge adapted to receive a volume of a body fluid, the cartridge comprising a plurality of sections, at least one of the sections adapted to react at least one reactant with the bodily fluid to form a pretreated sample; and an optics unit comprising at least one excitation illumination adapted to convey radiation to the pre-treated sample, at least one multi-spectral emission detector and at least one of a photon counter and an integrator, wherein the at least one excitation illumination and the at least one multi-spectral emission detector are disposed on the same side of the cartridge; and wherein the optics unit is adapted to detect a plurality of spectrally distinct signals generated by interaction of the radiation and the pre-treated sample in the cartridge, thereby determining said medical condition.