Patents by Inventor Meng-Chi Yen

Meng-Chi Yen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNAi compound targeted to thrombospondin-1 and applications thereof
    Patent number: 8377902
    Abstract: The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses. In addition, the present invention also disclosed that an RNAi compound targeted to Thrombospondin-1 gene can delay tumor progression.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: February 19, 2013
    Assignee: National Cheng Kung University
    Inventors: Ming-Derg Lai, Shih-Shien Huang, Meng-Chi Yen, Chi-Chen Lin, Tzu-Yang Weng
  • RNAi COMPOUND TARGETED TO THROMBOSPONDIN-1 AND APPLICATIONS THEREOF
    Publication number: 20110166199
    Abstract: The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses. In addition, the present invention also disclosed that an RNAi compound targeted to Thrombospondin-1 gene can delay tumor progression.
    Type: Application
    Filed: January 6, 2011
    Publication date: July 7, 2011
    Applicant: National Cheng Kung University
    Inventors: Ming-Derg Lai, Shih-Shien Huang, Meng-Chi Yen, Chi-Chen Lin, Tzu-Yang Weng