Abstract: An application of Bone Marrow Mesenchyml Stem Cell Exosomes (BMSC-Exos) in treating Parkinson's disease (PD) is provided, wherein the BMSC-Exos are generated by stimulating BMSCs with a culture solution and extracted from the culture solution after passage; and the culture solution of the BMSCs is an ?-MEM culture solution containing FBS and PS. The BMSC-Exos can greatly improve a motor function of a model mouse with PD, protect dopaminergic neurons of the model mouse with PD, improve an olfactory function of the model mouse with PD, and also inhibit the activation of olfactory astrocytes of the model mouse with PD.

Abstract: An application of Bone Marrow Mesenchyml Stem Cell Exosomes (BMSC-Exos) in treating Parkinson's disease (PD) is provided, wherein the BMSC-Exos are generated by stimulating BMSCs with a culture solution and extracted from the culture solution after passage; and the culture solution of the BMSCs is an ?-MEM culture solution containing FBS and PS. The BMSC-Exos can greatly improve a motor function of a model mouse with PD, protect dopaminergic neurons of the model mouse with PD, improve an olfactory function of the model mouse with PD, and also inhibit the activation of olfactory astrocytes of the model mouse with PD.

Abstract: A building based on a large-space structure body and a freestanding external envelope structure and a construction method, wherein the building comprises a structure body composed of a vertical-structure reinforced concrete member, a reinforced concrete girder and a reinforced concrete slab, and a freestanding combined external envelope system externally hung in a periphery of the structure body; and the structure body is made of a prefabricated combined reinforcement cage member poured with concrete, the prefabricated combined reinforcement cage member is combined and assembled by a prefabricated vertical-structure reinforcement cage member, a prefabricated girder reinforcement cage member and a prefabricated slab reinforcement cage member, and the prefabricated vertical-structure reinforcement cage member is a prefabricated shear wall reinforcement cage member or a prefabricated column reinforcement cage member.

Abstract: A building based on a large-space structure body and a freestanding external envelope structure and a construction method, wherein the building comprises a structure body composed of a vertical-structure reinforced concrete member, a reinforced concrete girder and a reinforced concrete slab, and a freestanding combined external envelope system externally hung in a periphery of the structure body; and the structure body is made of a prefabricated combined reinforcement cage member poured with concrete, the prefabricated combined reinforcement cage member is combined and assembled by a prefabricated vertical-structure reinforcement cage member, a prefabricated girder reinforcement cage member and a prefabricated slab reinforcement cage member, and the prefabricated vertical-structure reinforcement cage member is a prefabricated shear wall reinforcement cage member or a prefabricated column reinforcement cage member.