Patents by Inventor Meng-Shiue Wu

Meng-Shiue Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Decidual placental mesenchymal stem cell and the use of the cell for preparing pharmaceutical compositions for promoting angiogenesis
    Patent number: 11981925
    Abstract: Human decidual placental mesenchymal stem cell having an increased expression level of decoy receptor 3 (DcR3), and a method for obtaining the human decidual placental mesenchymal stem cells having an increased expression level of DcR3 are provided, wherein human decidual placental mesenchymal stem cells are cultured in a culture dish containing a serum-free medium and the DcR3 expression of the human decidual placental mesenchymal stem cells are increased by stimulation of at least one inflammatory cytokine for 48 hours, and obtaining the human decidual placental mesenchymal stem cells having an increased expression level of DcR3, wherein the increased expression level of DcR3 is significantly higher than that of human decidual placental mesenchymal stem cells with the stimulation is higher than that of human decidual placental mesenchymal stem cells cultured without the stimulation of the at least one inflammatory cytokine.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: May 14, 2024
    Assignee: BIOSPRING MEDICAL CO., LTD.
    Inventors: Li-Li Chu, Meng-Shiue Wu
  • Thermo-sensitive cell culture substrate having block copolymer
    Patent number: 11505633
    Abstract: A method of preparing PNVCL block polymers as the substrate for thermo-sensitive cultureware is provided. A hydrophobic polymer of poly n-butyl mathacrylate (PBMA) is obtained by atom transfer radical polymerization (ATRP) with typical haloalkane as an initiator. Further a thermo-sensitive block copolymer of poly n-vinyl caprolactam (PNVCL) is obtained by polymerization of N-vinyl caprolactam (NVCL) monomers using the hydrophobic PBMA polymer as a macroinitiator.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: November 22, 2022
    Assignee: QINGDAO AMA CO., LTD
    Inventors: Pei-Yen Wu, Zhenping Cheng, Thai-Yen Ling, Meng-Shiue Wu
  • METHOD OF PREPARING BLOCK COPOLYMER AND THERMO-SENSITIVE CELL CULTURE SUBSTRATE HAVING THE BLOCK COPOLYMER
    Publication number: 20210155728
    Abstract: A method of preparing PNVCL block polymers as the substrate for thermo-sensitive cultureware is provided. A hydrophobic polymer of poly n-butyl mathacrylate (PBMA) is obtained by atom transfer radical polymerization (ATRP) with typical haloalkane as an initiator. Further a thermo-sensitive block copolymer of poly n-vinyl caprolactam (PNVCL) is obtained by polymerization of N-vinyl caprolactam (NVCL) monomers using the hydrophobic PBMA polymer as a macroinitiator.
    Type: Application
    Filed: April 6, 2020
    Publication date: May 27, 2021
    Inventors: PEI-YEN WU, Zhenping Cheng, Thai-Yen Ling, Meng-Shiue Wu