Patents by Inventor Mengchao Chen

Mengchao Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141347
    Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu ZHANG, Xi CHEN, Zheng FU, Jing LI, Xiang ZHANG, Xinyan ZHOU, Li ZHANG, Mengchao YU, Hongyuan GUO
  • Publication number: 20240141361
    Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141344
    Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141380
    Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Patent number: 11961486
    Abstract: A display driving device configured to control a display panel including pixel units to display, includes: an over driver compensation module configured to, when a first polarity frame image is displayed, perform line over driver compensation on the pixel units based on line over driver compensation data corresponding to the first polarity frame image, to determine a target over driver grayscale of the pixel units; and to, when a second polarity frame image is displayed, perform line over driver compensation on the pixel units based on line over driver compensation data corresponding to the second polarity frame image, to determine a target over driver grayscale of the pixel units. The first and second polarity are opposite to each other, and the line over driver compensation data corresponding to the first polarity frame image is different from the line over driver compensation data corresponding to the second polarity frame image.
    Type: Grant
    Filed: October 28, 2021
    Date of Patent: April 16, 2024
    Assignees: Wuhan BOE Optoelectronics Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Lijun Xiao, Bing Li, Feng Jiang, Meng Feng, Mengchao Shuai, Hangyu Chen, Junmin Zhang
  • Publication number: 20240119912
    Abstract: The present disclosure provides a driving method for a liquid crystal display panel and a non-transitory computer storage medium. The driving method includes: for the plurality of sub-pixels, adopting a first gray-level table for displaying a picture in other frame pictures other than a first frame picture in each of the plurality of predetermined periods, the first gray-level table including a plurality of first gray-level values; and adopting a second gray-level table for displaying a picture in the first frame picture in each of the plurality of predetermined periods, the second gray-level table including a plurality of second gray-level values.
    Type: Application
    Filed: March 22, 2021
    Publication date: April 11, 2024
    Inventors: Hangyu CHEN, Lijun XIAO, Junmin ZHANG, Bing LI, Feng JIANG, Meng FENG, Mengchao SHUAI, Jianmin XIANG, Yun BAI
  • Publication number: 20230026397
    Abstract: A movable carbon capture system applied to agriculture-harmonious buildings, which includes a carbon capture unit and a high-concentration CO2 supply unit which are respectively integrated, wherein the carbon capture unit comprises a CO2 adsorption chamber and an air pump, and the high-concentration CO2 supply unit comprises a vacuum pump and an air storage cavity; an air inlet of the CO2 adsorption chamber is connected to the indoor environment, an exhaust port of the CO2 adsorption chamber is connected to an atmosphere outlet, an air outlet of the CO2 adsorption chamber is connected with an air inlet of the vacuum pump, an air outlet of the vacuum pump is connected with an air inlet of the air storage cavity, an air outlet of the air storage cavity is connected with a greenhouse air supply port, and the greenhouse air supply port is connected with a greenhouse.
    Type: Application
    Filed: July 22, 2021
    Publication date: January 26, 2023
    Inventors: Shuai Deng, Kailong WU, Bowen Liu, Li Zhao, Shuangjun Li, Mengchao Chen, Lijin Chen, Jie Zhao
  • Patent number: 11554343
    Abstract: A movable carbon capture system applied to agriculture-harmonious buildings, which includes a carbon capture unit and a high-concentration CO2 supply unit which are respectively integrated, wherein the carbon capture unit comprises a CO2 adsorption chamber and an air pump, and the high-concentration CO2 supply unit comprises a vacuum pump and an air storage cavity; an air inlet of the CO2 adsorption chamber is connected to the indoor environment, an exhaust port of the CO2 adsorption chamber is connected to an atmosphere outlet, an air outlet of the CO2 adsorption chamber is connected with an air inlet of the vacuum pump, an air outlet of the vacuum pump is connected with an air inlet of the air storage cavity, an air outlet of the air storage cavity is connected with a greenhouse air supply port, and the greenhouse air supply port is connected with a greenhouse.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: January 17, 2023
    Assignee: TIANJIN UNIVERSITY
    Inventors: Shuai Deng, Kailong Wu, Bowen Liu, Li Zhao, Shuangjun Li, Mengchao Chen, Lijin Chen, Jie Zhao