Patents by Inventor Meng-Fen Ho

Meng-Fen Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING GLUCAGON-LIKE PEPTIDE-1
    Publication number: 20230406900
    Abstract: The present disclosure provides an improved process for the preparation of glucagon-like peptide-1 agonist peptide. Specifically, it relates to a manufacturing process useful for reducing impurities and increasing the yields and the balance of cost in the preparation of liraglutide or semaglutide.
    Type: Application
    Filed: May 17, 2023
    Publication date: December 21, 2023
    Inventors: Ming-Chih Wu, Meng-Fen Ho, Tsung-Yu Hsiao
  • PROCESS FOR PREPARING RELUGOLIX AND INTERMEDIATES THEREOF
    Publication number: 20230357267
    Abstract: The present disclosure provides improved processes for the preparation of Relugolix and intermediates thereof. Relugolix is prepared via intermediates (M7) and (M8): wherein X is as described herein. Present disclosure also provides three additional routes to prepare Relugolix and intermediates thereof, where the starting material of ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate (SM1) is protected by coupling with an acyl chloride, a hydroxylamine or an oxime.
    Type: Application
    Filed: May 4, 2023
    Publication date: November 9, 2023
    Inventors: Yung-Hung CHANG, Tsung-Yu HSIAO, Meng-Fen HO
  • Process for preparation of cangrelor tetrasodium and intermediate therefor
    Publication number: 20190241606
    Abstract: A process for preparing cangrelor tetrasodium comprising: a) reacting a compound of formula M1 with morpholine to form a compound of formula M2; and b) reacting the compound of formula M2 with clodronic acid to provide cangrelor tetrasodium
    Type: Application
    Filed: February 5, 2018
    Publication date: August 8, 2019
    Inventors: Tsung-Yu Hsiao, Chen-Wei Lin, Yu-Hui Huang, Meng-Fen Ho, Kuan-Hsun Wang
  • Crystalline and non-crystalline forms of SGLT2 inhibitors
    Patent number: 8999941
    Abstract: The present invention provides amorphous forms and the crystalline complexes of SGLT2 inhibitors as a novel material, in particular in pharmaceutically acceptable form. The crystalline forms of SGLT2 inhibitor canagliflozin are designated as Forms CS1, CS2, CS3, CS4 and CS5.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: April 7, 2015
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: Julian Paul Henschke, Meng-Fen Ho, Shu-Ping Chen, Yung-Fa Chen
  • CRYSTALLINE AND NON-CRYSTALLINE FORMS OF SGLT2 INHIBITORS
    Publication number: 20130237487
    Abstract: The present invention provides amorphous forms and the crystalline complexes of SGLT2 inhibitors as a novel material, in particular in pharmaceutically acceptable form. The crystalline forms of SGLT2 inhibitor canagliflozin are designated as Forms CS1, CS2, CS3, CS4 and CS5.
    Type: Application
    Filed: October 30, 2012
    Publication date: September 12, 2013
    Applicant: Scinopharm Taiwan, LTD.
    Inventors: Julian Paul Henschke, Meng-Fen Ho, Shu-Ping Chen, Yung-Fa Chen
  • Crystalline forms of docetaxel and process for preparation thereof
    Patent number: 8357811
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: January 22, 2013
    Assignee: ScnioPharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao
  • Synthesis of glatiramer acetate
    Patent number: 8212002
    Abstract: A process of making a polylpeptide or a pharmaceutically acceptable salt thereof comprises reacting a L-lysine protected polypeptide, which comprises L-alanine, L-tyrosine, L-glutamate, and L-lysine that is protected with a protecting group, with a tetraalkylammonium hydroxide in water to remove the protecting group.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: July 3, 2012
    Assignee: Scinopharm Taiwan Ltd
    Inventors: Tsung-Yu Hsiao, Meng-Fen Ho
  • Crystalline forms of docetaxel and process for preparation thereof
    Patent number: 7662980
    Abstract: Anbydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: February 16, 2010
    Assignee: Scinopharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao
  • Synthesis of Glatiramer Acetate
    Publication number: 20100036092
    Abstract: A process of making a polylpeptide or a pharmaceutically acceptable salt thereof comprises reacting a L-lysine protected polypeptide, which comprises L-alanine, L-tyrosine, L-glutamate, and L-lysine that is protected with a protecting group, with a tetraalkylammonium hydroxide in water to remove the protecting group.
    Type: Application
    Filed: August 5, 2009
    Publication date: February 11, 2010
    Inventors: Tsung-Yu Hsiao, Meng-Fen Ho
  • Crystalline Forms of Docetaxel and process for Preparation Thereof
    Publication number: 20090275762
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Application
    Filed: July 13, 2009
    Publication date: November 5, 2009
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Ll Lin, Tsung-Yu Hsiao
  • Crystalline forms of docetaxel and process for preparation thereof
    Publication number: 20080108693
    Abstract: New anhydrous crystalline form of docetaxel and process of making anhydrous docetaxel and docetaxel trihydrate are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 8, 2008
    Applicant: Scinopharm Singapore PTE Ltd.
    Inventors: Yuan-Xiu Liao, Meng-Fen Ho, Shu-Ping Chen, Chia-Ning Lin, Yu-Li Lin, Tsung-Yu Hsiao