Patents by Inventor Mengjiao LIU

Mengjiao LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 15-benzylidene-14-deoxy-11, 12-dehydroandrographolide derivative in manufacture of medicaments for protecting liver and anti-hepatitis C virus
    Patent number: 9388169
    Abstract: Disclosed is use of andrographolide derivative as shown by general formula 1 in manufacture of medicaments for anti-hepatitis C virus, and preventing and treating immunological liver damage caused by virus infection and different chemical liver damage.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: July 12, 2016
    Assignee: Zhengzho University
    Inventors: Guifu Dai, Songlin Zhu, Yanan Wang, Jian Wu, Dan Zhao, Di Wu, Huanfei Liu, Haiwei Xu, Mengjiao Liu, Jing Zhao, Wei Han, Zhenwei Wu, Hang Wang, Hongmin Liu
  • Use of 15-benzylidene-14-deoxy-11, 12-dehydroandrographolide derivative in manufacture of medicaments for protecting liver and anti-hepatitis C virus
    Publication number: 20150051403
    Abstract: Disclosed is use of andrographolide derivative as shown by general formula 1 in manufacture of medicaments for anti-hepatitis C virus, and preventing and treating immunological liver damage caused by virus infection and different chemical liver damage.
    Type: Application
    Filed: February 5, 2013
    Publication date: February 19, 2015
    Applicant: ZHENGZHOU UNIVERSITY
    Inventors: Guifu Dai, Songlin Zhu, Yanan Wang, Jian Wu, Dan Zhao, Di Wu, Huanfei Liu, Haiwei Xu, Mengjiao Liu, Jing Zhao, Wei Han, Zhenwei Wu, Hang Wang, Hongmin Liu
  • USES OF C15-SUBSTITUTED ANDROGRAPHOLIDE DERIVATIVES IN THE PREPARATION OF ANTI-HEPATITIS B VIRUS MEDICAMENT
    Publication number: 20140187627
    Abstract: Disclosed is a use of C15-substituted andrographolide derivatives in preparation of anti-hepatitis B virus medicaments. In the present invention, the HepG2.2.15 cells are used to measure the amount of the hepatitis B virus surface antigen (HBsAg) secretion in the supernatant of the culture; the duck hepatitis B virus (DHBV) is used to infect the model and the DHBV-DNA level in serum is measured, and the pathological change in hepatic tissue is observed. A number of andrographolide derivative compounds are screened, compounds having a good anti-HBV effect are preferred, which has a structure represented by general formula 1 set forth herein. Due to high anti-HBV activity and low toxicity, as well as good protection against hepatic injury, the compounds can be used as the active ingredient for preparing anti-HBV medicaments, thereby providing a new pharmaceutical way for treatment of hepatitis, and broadening the range of clinical medicines.
    Type: Application
    Filed: July 3, 2012
    Publication date: July 3, 2014
    Applicant: ZHENGZHOU UNIVERSITY
    Inventors: Guifu DAI, Haiwei XU, Zhiwen JIANG, Hongmin LIU, Yanan WANG, Kuicheng ZHU, Zhenwei WU, Weiyi LI, Fengjuan WU, Mengjiao LIU, Wei HAN