Patents by Inventor Mengru Chen

Mengru Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260069647
    Abstract: A traditional Chinese medicine (TCM) compound composition for treating heart failure (HF) includes Semen Sinapis Albae, Radix Kansui Praeparata, Semen Descurainiae, Ramulus Cinnamomi, Radix Aconiti Lateralis Praeparata, Eupolyphaga Steleophaga, Cortex Moutan, and Rhizoma Smilacis Glabrae. An acupoint selection principle for the external application of a YANG-warming and heart-settling plaster focuses on warming and tonifying the heart and kidneys, promoting blood circulation, and dispelling water retention. Five acupoints are selected: Danzhong (CV17), Xinshu (BL15), Juque (CV14), Shenshu (BL23), and Jingmen (GB25). Among these, Xinshu (BL15) paired with Juque (CV14), and Shenshu (BL23) paired with Jingmen (GB25), form combinations for the heart and kidneys for the heart and kidneys, facilitating tonification of the heart and kidneys, promoting water drainage to resolve dampness, and activating blood circulation to unblock meridians.
    Type: Application
    Filed: September 3, 2025
    Publication date: March 12, 2026
    Inventors: Lan Ge, Xiaoyu Cheng, Zhenpeng Zhu, Zhongzhi Li, Wenjun Jiang, Dan Cheng, Yulong Liu, Xinyue Wang, Maomao Zhang, Xiaowen Ma, Mengzhao Wei, Sheng Sheng, Mengru Chen
  • Publication number: 20250358545
    Abstract: A method for reducing routing between modules, a signal transmission method and apparatus, and an image sensor are provided. The method includes: determining a first signal line and at least one second signal line that are capable of being multiplexed, wherein the first signal line is used to transmit a first signal, and the second signal line is used to transmit a second signal; determining time-division control logic; connecting two terminals of the at least one second signal line to two terminals of the first signal line, respectively, and deleting the at least one second signal line; and controlling to transmit the first signal and the second signal on the first signal line according to the time-division control logic. Embodiments of the present disclosure may effectively reduce a number of routings between modules, thereby reducing a chip size and improving miniaturization of a device.
    Type: Application
    Filed: October 9, 2022
    Publication date: November 20, 2025
    Applicant: GALAXYCORE SHANGHAI LIMITED CORPORATION
    Inventors: Mengru CHEN, Qianqian JI, Xin ZHOU
  • Patent number: 11930649
    Abstract: A transparent top electrode composite film for organic optoelectronic devices includes a substrate, an MoOx film layer coated on the substrate, a doped Ag-based film layer coated on the MoOx film layer and an HfOx film layer coated on the doped Ag-based film layer. A preparation method of the transparent top electrode composite film, which is achieved under vacuum and low temperature, includes steps of (A) depositing an MoOx film layer on a substrate through thermal evaporation process or electron beam evaporation process without heating the substrate; (B) depositing a doped Ag-based film layer on the MoOx film layer through sputtering process or evaporation process; and (C) depositing an HfOx film layer on the doped Ag-based film layer through reactive sputtering process, thereby obtaining the transparent top electrode composite film. The composite film is able to be used as a top electrode material for organic optoelectronic devices.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: March 12, 2024
    Assignee: University of Electronic Science and Technology of China
    Inventors: Deen Gu, Xin Zhou, Yadong Jiang, Mengru Chen
  • Patent number: 11548918
    Abstract: A sodium channel protein Nav1.4-targeting polypeptide is disclosed, which has an amino acid sequence of SEQ ID NO:1. The polypeptide includes a first disulfide bond between Cys-3 and Cys-17, a second disulfide bond between Cys-4 and Cys-23, and a third disulfide bond between Cys-12 and Cys-24. The polypeptide has a complex coiled structure consisting of a main chain and disulfide bonds, in which three key residues LYS10, ARG18, and ARG22 could interact with Nav1.4 and be essential to block its penetrability of sodium. The polypeptide can target sodium channel protein Nav1.4 to form a stable protein complex; compared with naturally extracted drugs, the polypeptide Nav1.4 is superior in terms of yield, production, and cost saving, making it a promising Nav-targeting drug with broad application prospects.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: January 10, 2023
    Inventor: Mengru Chen
  • Publication number: 20220242915
    Abstract: A sodium channel protein Nav1.4-targeting polypeptide is disclosed, which has an amino acid sequence of SEQ ID NO:1. The polypeptide includes a first disulfide bond between Cys-3 and Cys-17, a second disulfide bond between Cys-4 and Cys-23, and a third disulfide bond between Cys-12 and Cys-24. The polypeptide has a complex coiled structure consisting of a main chain and disulfide bonds, in which three key residues LYS10, ARG18, and ARG22 could interact with Nav1.4 and be essential to block its penetrability of sodium. The polypeptide can target sodium channel protein Nav1.4 to form a stable protein complex; compared with naturally extracted drugs, the polypeptide Nav1.4 is superior in terms of yield, production, and cost saving, making it a promising Nav-targeting drug with broad application prospects.
    Type: Application
    Filed: May 25, 2021
    Publication date: August 4, 2022
    Inventor: Mengru CHEN
  • Publication number: 20220123243
    Abstract: A transparent top electrode composite film for organic optoelectronic devices includes a substrate, an MoOx film layer coated on the substrate, a doped Ag-based film layer coated on the MoOx film layer and an HfOx film layer coated on the doped Ag-based film layer. A preparation method of the transparent top electrode composite film, which is achieved under vacuum and low temperature, includes steps of (A) depositing an MoOx film layer on a substrate through thermal evaporation process or electron beam evaporation process without heating the substrate; (B) depositing a doped Ag-based film layer on the MoOx film layer through sputtering process or evaporation process; and (C) depositing an HfOx film layer on the doped Ag-based film layer through reactive sputtering process, thereby obtaining the transparent top electrode composite film. The composite film is able to be used as a top electrode material for organic optoelectronic devices.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 21, 2022
    Inventors: Deen Gu, Xin Zhou, Yadong Jiang, Mengru Chen