Patents by Inventor Mengru Chen

Mengru Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250068700
    Abstract: A method and an apparatus for few-shot relation classification and filtering, and a device are provided. The method includes: constructing a coarse-grained filter for filtering an unlabeled corpus to obtain candidate instances with a same entity as a seed instance and with similar semantics to the seed instance; constructing a fine-grained filter for filtering the candidate instances to obtain a candidate instance with a same relation concept as the seed instance; defining the candidate instance as a positive instance set, and defining candidate instances with different relation concepts from the seed instance as a negative sample set; constructing a false positive instance correction module for adjusting and controlling a proportion of the negative sample set used by a classifier during training; training the classifier based on a small number of obtained labeled instances belonging to a newly emerging relation and the adjusted positive instance set and negative sample set.
    Type: Application
    Filed: August 26, 2024
    Publication date: February 27, 2025
    Inventors: Fei CAI, Peihong Li, Honghui Chen, Jianming Zheng, Taihua Shao, Mengru Wang, Siyuan Wang, Dengfeng Liu, Yanying Mao
  • Patent number: 11930649
    Abstract: A transparent top electrode composite film for organic optoelectronic devices includes a substrate, an MoOx film layer coated on the substrate, a doped Ag-based film layer coated on the MoOx film layer and an HfOx film layer coated on the doped Ag-based film layer. A preparation method of the transparent top electrode composite film, which is achieved under vacuum and low temperature, includes steps of (A) depositing an MoOx film layer on a substrate through thermal evaporation process or electron beam evaporation process without heating the substrate; (B) depositing a doped Ag-based film layer on the MoOx film layer through sputtering process or evaporation process; and (C) depositing an HfOx film layer on the doped Ag-based film layer through reactive sputtering process, thereby obtaining the transparent top electrode composite film. The composite film is able to be used as a top electrode material for organic optoelectronic devices.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: March 12, 2024
    Assignee: University of Electronic Science and Technology of China
    Inventors: Deen Gu, Xin Zhou, Yadong Jiang, Mengru Chen
  • Patent number: 11548918
    Abstract: A sodium channel protein Nav1.4-targeting polypeptide is disclosed, which has an amino acid sequence of SEQ ID NO:1. The polypeptide includes a first disulfide bond between Cys-3 and Cys-17, a second disulfide bond between Cys-4 and Cys-23, and a third disulfide bond between Cys-12 and Cys-24. The polypeptide has a complex coiled structure consisting of a main chain and disulfide bonds, in which three key residues LYS10, ARG18, and ARG22 could interact with Nav1.4 and be essential to block its penetrability of sodium. The polypeptide can target sodium channel protein Nav1.4 to form a stable protein complex; compared with naturally extracted drugs, the polypeptide Nav1.4 is superior in terms of yield, production, and cost saving, making it a promising Nav-targeting drug with broad application prospects.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: January 10, 2023
    Inventor: Mengru Chen
  • Publication number: 20220242915
    Abstract: A sodium channel protein Nav1.4-targeting polypeptide is disclosed, which has an amino acid sequence of SEQ ID NO:1. The polypeptide includes a first disulfide bond between Cys-3 and Cys-17, a second disulfide bond between Cys-4 and Cys-23, and a third disulfide bond between Cys-12 and Cys-24. The polypeptide has a complex coiled structure consisting of a main chain and disulfide bonds, in which three key residues LYS10, ARG18, and ARG22 could interact with Nav1.4 and be essential to block its penetrability of sodium. The polypeptide can target sodium channel protein Nav1.4 to form a stable protein complex; compared with naturally extracted drugs, the polypeptide Nav1.4 is superior in terms of yield, production, and cost saving, making it a promising Nav-targeting drug with broad application prospects.
    Type: Application
    Filed: May 25, 2021
    Publication date: August 4, 2022
    Inventor: Mengru CHEN
  • Publication number: 20220123243
    Abstract: A transparent top electrode composite film for organic optoelectronic devices includes a substrate, an MoOx film layer coated on the substrate, a doped Ag-based film layer coated on the MoOx film layer and an HfOx film layer coated on the doped Ag-based film layer. A preparation method of the transparent top electrode composite film, which is achieved under vacuum and low temperature, includes steps of (A) depositing an MoOx film layer on a substrate through thermal evaporation process or electron beam evaporation process without heating the substrate; (B) depositing a doped Ag-based film layer on the MoOx film layer through sputtering process or evaporation process; and (C) depositing an HfOx film layer on the doped Ag-based film layer through reactive sputtering process, thereby obtaining the transparent top electrode composite film. The composite film is able to be used as a top electrode material for organic optoelectronic devices.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 21, 2022
    Inventors: Deen Gu, Xin Zhou, Yadong Jiang, Mengru Chen