Patents by Inventor Mengshi Zhang

Mengshi Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250067756
    Abstract: An enzyme-linked immunosorbent assay (ELISA) method and a monoclonal antibody for giant panda relaxin-3 (RLN3) are provided. The method includes: conducting ELISA with an anti-giant panda RLN3 monoclonal antibody as a coating antibody and an anti-RLN3 polyclonal antibody as a labeling antibody, where the anti-giant panda RLN3 monoclonal antibody is secreted by a hybridoma cell line RLN-3; and the hybridoma cell line RLN-3 was deposited in the China Center for Type Culture Collection (CCTCC) of Wuhan University, Wuhan, China on Jan. 7, 2021, with an accession number of CCTCC NO: C202129. In addition, an ELISA method for detecting RLN3 in giant panda urine is developed, in which a prepared anti-giant panda RLN3 monoclonal antibody is used as a coating antibody and an anti-giant panda RLN3 polyclonal antibody is used as a labeling antibody. The method can monitor a change in giant panda RLN3 timely by determining giant panda RLN3.
    Type: Application
    Filed: August 19, 2024
    Publication date: February 27, 2025
    Applicant: Chengdu Research Base of Giant Panda Breeding
    Inventors: Kailai CAI, Rong HOU, Yuliang LIU, Jingchao LAN, Mingxi LI, Juan WANG, Mengshi ZHANG, Shenfei WANG, Feiping LI, Xianbiao HU
  • Patent number: 12180273
    Abstract: The present invention discloses an anti-giant panda LIF monoclonal antibody, a hybridoma cell line, and use thereof, and belongs to the field of biotechnology. The antibody comprises a heavy chain variable region having an amino acid sequence set forth in SEQ ID NO. 1 and a light chain variable region having an amino acid sequence set forth in SEQ ID NO. 2. The hybridoma cell line LIF-2 is deposited at China Center for Type Culture Collection on Oct. 28, 2021 with the accession number of CCTCC NO: C202171. The anti-giant panda LIF monoclonal antibody developed by the present invention can accurately identify the target protein LIF, and lays an important foundation for LIF protein localization, tissue expression information, study on LIF and a receptor and a target cell thereof by using the high-specificity LIF monoclonal antibody and exploration of the effect of LIF in embryonic diapause in giant pandas.
    Type: Grant
    Filed: March 20, 2024
    Date of Patent: December 31, 2024
    Assignee: Chengdu Research Base of Giant Panda Breeding
    Inventors: Kailai Cai, Rong Hou, Yuliang Liu, Jingchao Lan, Mengshi Zhang, Feiping Li, Shenfei Wang, Xianbiao Hu, Juan Wang, Mingyue Zhang
  • Publication number: 20240383977
    Abstract: The present invention discloses an anti-giant panda LIF monoclonal antibody, a hybridoma cell line, and use thereof, and belongs to the field of biotechnology. The antibody comprises a heavy chain variable region having an amino acid sequence set forth in SEQ ID NO. 1 and a light chain variable region having an amino acid sequence set forth in SEQ ID NO. 2. The hybridoma cell line LIF-2 is deposited at China Center for Type Culture Collection on Oct. 28, 2021 with the accession number of CCTCC NO: C202171. The anti-giant panda LIF monoclonal antibody developed by the present invention can accurately identify the target protein LIF, and lays an important foundation for LIF protein localization, tissue expression information, study on LIF and a receptor and a target cell thereof by using the high-specificity LIF monoclonal antibody and exploration of the effect of LIF in embryonic diapause in giant pandas.
    Type: Application
    Filed: March 20, 2024
    Publication date: November 21, 2024
    Inventors: KAILAI CAI, RONG HOU, YULIANG LIU, JINGCHAO LAN, MENGSHI ZHANG, FEIPING LI, SHENFEI WANG, XIANBIAO HU, JUAN WANG, MINGYUE ZHANG
  • Patent number: 11867778
    Abstract: The present disclosure discloses a system and method for testing the spatial distribution uniformity of an alkali metal atom number density of an atom magnetometer. The system includes a detection laser, a laser beam expanding system, a polarizing element, a magnetic shielding system, an alkali metal atom gas chamber, a beam profile camera, a beam splitting prism, etc., which are sequentially arranged in a light advancing direction. In the method, based on an optical absorption principle, light intensity attenuations of linearly polarized light before and after passing through the alkali metal gas chamber are tested by using the beam profile camera with pixels in the level of um, a two-dimensional distribution matrix of an atom number density in space is calculated, and the distribution uniformity of the atom number density is analyzed by using a discrete coefficient.
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: January 9, 2024
    Assignee: ZHEJIANG LAB
    Inventors: Qiang Guo, Ning Zhang, Ziwen Li, Zixuan Wang, Mengshi Zhang, Tingting Yu
  • Publication number: 20230092597
    Abstract: The present disclosure discloses a system and method for testing the spatial distribution uniformity of an alkali metal atom number density of an atom magnetometer. The system includes a detection laser, a laser beam expanding system, a polarizing element, a magnetic shielding system, an alkali metal atom gas chamber, a beam profile camera, a beam splitting prism, etc., which are sequentially arranged in a light advancing direction. In the method, based on an optical absorption principle, light intensity attenuations of linearly polarized light before and after passing through the alkali metal gas chamber are tested by using the beam profile camera with pixels in the level of um, a two-dimensional distribution matrix of an atom number density in space is calculated, and the distribution uniformity of the atom number density is analyzed by using a discrete coefficient.
    Type: Application
    Filed: August 17, 2022
    Publication date: March 23, 2023
    Inventors: Qiang GUO, Ning ZHANG, Ziwen LI, Zixuan WANG, Mengshi ZHANG, Tingting YU
  • Publication number: 20190137971
    Abstract: The present application discloses a method and an apparatus for editing, obtaining, and protecting a process of a solar cell production device. The editing method comprises: storing, hardware information of production devices on a solar cell production line on a process editing terminal; editing, on the process editing terminal, process data of a specified production device by using a process editor; and encrypting the process data according to hardware information that is of the specified production device and that is stored on the process editing terminal and an encryption method, to obtain a process file of the specified production device. The possibility of obtaining process data by people around the production device is effectively reduced, and the process file is not easily cracked, thereby greatly improving the data security.
    Type: Application
    Filed: September 22, 2018
    Publication date: May 9, 2019
    Inventors: Mengshi ZHANG, Bin YANG
  • Publication number: 20190057886
    Abstract: A temperature measuring method and system for a thin film solar cell process device are provided. The method includes: sending a temperature measuring apparatus into a feeding chamber, a heating chamber, a process chamber, a cooling chamber and a discharging chamber of the thin film solar cell process device in sequence, and measuring and storing a current temperature of each heating zone in the heating chamber, the process chamber and the cooling chamber in sequence; and comparing the current temperature with a preset temperature, and adjusting a heating temperature of a heater of each heating zone in the heating chamber, the process chamber and the cooling chamber according to a comparison result.
    Type: Application
    Filed: August 16, 2018
    Publication date: February 21, 2019
    Inventor: Mengshi Zhang