Patents by Inventor Mengtian ZHANG

Mengtian ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11547715
    Abstract: A drug that contains chlorogenic acid is effective in treating chordoma. When administered to a patient in need thereof, chlorogenic acid can significantly inhibit the proliferation of chordoma cells, reduce the expression level of multi-drug resistance gene MDR1 of chordoma cells, reverse the multi-drug resistance of chordoma cells, and effectively treat chordoma disease.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: January 10, 2023
    Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Jie Zhang, Yazhuo Zhang, Mengtian Zhang
  • Patent number: 11135160
    Abstract: Provided are a use of chlorogenic acid in preparing pharmaceuticals for the inhibition of LAG-3 and a use of chlorogenic acid in preparing pharmaceuticals for the treatment of LAG-3-mediated diseases. The inhibition of LAG-3 by chlorogenic acid is useful in cancer therapy, anti-viral therapy, and sepsis treatment. The oral bioavailability of chlorogenic acid is enhanced by preparing chlorogenic acid as a gastric floating tablet.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: October 5, 2021
    Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD
    Inventors: Jie Zhang, Xiaoguang Chen, Nina Xue, Mengtian Zhang
  • Publication number: 20200338104
    Abstract: A drug that contains chlorogenic acid is effective in treating chordoma. When administered to a patient in need thereof, chlorogenic acid can significantly inhibit the proliferation of chordoma cells, reduce the expression level of multi-drug resistance gene MDR1 of chordoma cells, reverse the multi-drug resistance of chordoma cells, and effectively treat chordoma disease.
    Type: Application
    Filed: December 27, 2018
    Publication date: October 29, 2020
    Inventors: Jie ZHANG, Yazhuo ZHANG, Mengtian ZHANG
  • Publication number: 20190175499
    Abstract: Provided are a use of chlorogenic acid in preparing pharmaceuticals for the inhibition of LAG-3 and a use of chlorogenic acid in preparing pharmaceuticals for the treatment of LAG-3-mediated diseases. The inhibition of LAG-3 by chlorogenic acid is useful in cancer therapy, anti-viral therapy, and sepsis treatment.
    Type: Application
    Filed: February 20, 2017
    Publication date: June 13, 2019
    Inventors: Jie ZHANG, Xiaoguang CHEN, Nina XUE, Mengtian ZHANG