Patents by Inventor Mengxie Jin

Mengxie Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and preparation thereof
    Patent number: 11591409
    Abstract: Provided are an anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and a preparation thereof. In particular, provided are a highly stable heterodimeric anti-PD-L1/anti-PD-1 bispecific antibody with characteristics of a natural IgG and without mismatches heavy chain-light chain, and a preparation thereof. The bispecific antibody can bind to both target molecules and is more effective in treating a complex disease.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: February 28, 2023
    Assignee: BEIJING HANMI PHARM. CO., LTD.
    Inventors: Jiawang Liu, Nanmeng Song, Yaping Yang, Mengxie Jin
  • Antibody specifically binding to PD-1 and functional fragment thereof
    Patent number: 11117967
    Abstract: An antibody specifically binding to PD-1 and a functional fragment thereof. The antibody or functional fragment thereof includes a PD-1 chimeric antibody and a functional fragment thereof, and a PD-1 humanized antibody and a functional fragment thereof.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: September 14, 2021
    Assignee: BEIJING HANMI PHARM. CO., LTD.
    Inventors: Yaping Yang, Jiawang Liu, Nanmeng Song, Hongjuan Zhang, Mengxie Jin
  • Antibody specifically binding to IL-17A, encoding nucleic acid, and method of using the antibody
    Patent number: 11072651
    Abstract: An antibody specifically binding to IL-17A or a functional fragment thereof. The antibody or functional fragment thereof includes an IL-17A chimeric antibody and a functional fragment thereof, and an IL-17A humanized antibody and a functional fragment thereof.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: July 27, 2021
    Assignee: BEIJING HANMI PHARM. CO., LTD.
    Inventors: Nanmeng Song, Jiawang Liu, Yaping Yang, Yang Yang, Dongge Yang, Hongjuan Zhang, Mengxie Jin
  • ANTI-PD-L1/ANTI-PD-1 NATURAL ANTIBODY STRUCTURE-LIKE HETERODIMERIC BISPECIFIC ANTIBODY AND PREPARATION THEREOF
    Publication number: 20200299412
    Abstract: Provided are an anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and a preparation thereof. In particular, provided are a highly stable heterodimeric anti-PD-L1/anti-PD-1 bispecific antibody with characteristics of a natural IgG and without mismatches heavy chain-light chain, and a preparation thereof. The bispecific antibody can bind to both target molecules and is more effective in treating a complex disease.
    Type: Application
    Filed: March 28, 2018
    Publication date: September 24, 2020
    Applicant: BEIJING HANMI PHARM. CO., LTD.
    Inventors: Jiawang Liu, Nanmeng Song, Yaping Yang, Mengxie Jin
  • ANTIBODY SPECIFICALLY BINDING TO PD-1 AND FUNCTIONAL FRAGMENT THEREOF
    Publication number: 20190367615
    Abstract: An antibody specifically binding to PD-1 and a functional fragment thereof. The antibody or functional fragment thereof includes a PD-1 chimeric antibody and a functional fragment thereof, and a PD-1 humanized antibody and a functional fragment thereof.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 5, 2019
    Inventors: Yaping Yang, Jiawang Liu, Nanmeng Song, Hongjuan Zhang, Mengxie Jin
  • ANTIBODY SPECIFICALLY BINDING TO IL-17A AND FUNCTIONAL FRAGMENT THEREOF
    Publication number: 20190256588
    Abstract: An antibody specifically binding to IL-17A or a functional fragment thereof. The antibody or functional fragment thereof includes an IL-17A chimeric antibody and a functional fragment thereof, and an IL-17A humanized antibody and a functional fragment thereof.
    Type: Application
    Filed: September 8, 2017
    Publication date: August 22, 2019
    Inventors: Nanmeng Song, Jiawang Liu, Yaping Yang, Yang Yang, Dongge Yang, Hongjuan Zhang, Mengxie Jin