Patents by Inventor Menno Frederik Kielman

Menno Frederik Kielman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEANS AND METHODS FOR ELICITING AN IMMUNE RESPONSE
    Publication number: 20100313284
    Abstract: The invention provides means and methods for immunizing an animal against an antigen of interest, using stem cells, progenitor cells and/or dedifferentiated cells.
    Type: Application
    Filed: October 31, 2008
    Publication date: December 9, 2010
    Applicant: DeltaCell B.V.
    Inventor: Menno Frederik Kielman
  • Inhibition of stem cell differentiation, enhancement of proliferation and selective induction of apoptosis by Wnt factors
    Publication number: 20100203634
    Abstract: The invention relates to a method for at least in part inhibiting differentiation of stem cells in a population of mammalian cells comprising up-regulating a Wnt-signaling pathway to a differentiation-inhibiting level in the population of cells. The invention increases at the same time the number of stem cells in a population of mammalian cells compared to a reference population, and induces, at least in part, apoptosis in mesenchymal cells in a population of mammalian cells. The invention also discloses a method for selective differentiation of a stem cell, comprising controlling the level of Wnt pathway activation. The invention is used for the proliferation and subsequent differentiation of embryonic stem cells and lung stem cells, and for ex vivo lung explant cultivation.
    Type: Application
    Filed: March 19, 2010
    Publication date: August 12, 2010
    Applicant: DeltaCell B.V.
    Inventor: Menno Frederik Kielman