Patents by Inventor Menno Van Lookeren Campagne

Menno Van Lookeren Campagne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of CRIg and C3b:CRIg complex
    Patent number: 7776573
    Abstract: The present invention concerns determination of the crystal structure of the macrophage specific receptor, CRIg (earlier referred to as STIgMA), and its complex with the C3b and C3c subunits of complement C3 (C3b:CRIg and C3c:CRIg complexes). The invention further concerns the use of the crystal structure of CRIg or the C3b:CRIg complex to screen for and identify molecules structurally and/or functionally related to CRIg, including CRIg agonists and antagonists.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: August 17, 2010
    Assignee: Genentech, Inc.
    Inventors: Philip Hass, Jianping Yin, Kenneth Katschke, Micah Steffek, Menno Van Lookeren Campagne, Christian Wiesmann
  • Affinity matured CRIg variants
    Publication number: 20100150908
    Abstract: The present invention concerns affinity matured CRIg variants. In particular, the invention concerns CRIg variants having increased binding affinity to C3b and retaining selective binding to C3b over C3.
    Type: Application
    Filed: May 6, 2009
    Publication date: June 17, 2010
    Inventors: Sachdev S. Sidhu, Bing Li, Menno Van Lookeren Campagne, Christian Wiesmann
  • HUMANIZED ANTI-FACTOR D ANTIBODIES AND USES THEREOF
    Publication number: 20090269338
    Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Application
    Filed: April 27, 2009
    Publication date: October 29, 2009
    Applicant: Genentech, Inc.
    Inventors: Arthur Huang, Robert Kelley, Henry Lowman, Menno Van Lookeren Campagne, Charles Winter
  • Prevention and treatment of complement-associated eye conditions
    Publication number: 20090181017
    Abstract: The invention concerns the prevention and treatment of complement-associated eye conditions, such as choroidal neovascularization (CNV) and age-related macular degeneration (AMD), by administration of Factor D antagonists.
    Type: Application
    Filed: May 22, 2008
    Publication date: July 16, 2009
    Inventors: Philip Hass, Yin Jianping, Kenneth Katschke, JR., Micah Steffek, Christian Wiesmann, Menno Van Lookeren Campagne
  • CRIg antagonists
    Publication number: 20090162356
    Abstract: The present invention concerns blocking antibodies specifically binding a recently discovered macrophage specific receptor, CRIg, and their use to prevent cellular entry of intracellular pathogens, such as viruses, bacteria or parasites as well as for prevention of unwanted clearance of erythrocytes and platelets.
    Type: Application
    Filed: April 25, 2008
    Publication date: June 25, 2009
    Inventor: Menno Van Lookeren Campagne
  • Anti-factor B antibodies and their uses
    Publication number: 20090123469
    Abstract: The invention concerns the prevention and treatment of complement-associated eye conditions, such as choroidal neovascularization (CNV) and age-related macular degeneration (AMD), by administration of factor B antagonists.
    Type: Application
    Filed: November 6, 2008
    Publication date: May 14, 2009
    Inventors: Menno Van Lookeren Campagne, Laura Deforge
  • C3b antibodies and methods for the prevention and treatment of complement-associated disorders
    Publication number: 20090081211
    Abstract: The present invention concerns antibodies to C3b and the prevention and treatment of complement-associated disorder using such antibodies.
    Type: Application
    Filed: June 6, 2008
    Publication date: March 26, 2009
    Inventor: Menno Van Lookeren Campagne