Patents by Inventor Mercedes Gonzalez-Juarrero

Mercedes Gonzalez-Juarrero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical probes to identify anti-mycobacterial MmpL3 inhibitors
    Patent number: 11608328
    Abstract: The present application provides detectable compounds useful for identifying compounds that bind (e.g., inhibit) MmpL3. Methods of identifying compounds that bind and/or inhibit MmpL3 are also provided.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: March 21, 2023
    Assignees: Creighton University, Colorado State University Research Foundation
    Inventors: E. Jeffrey North, Amitkumar Navinchandra Pandya, Mary C. Jackson, Wei Li, Mercedes Gonzalez-Juarrero
  • Chemical Probes to Identify Anti-Mycobacterial MmpL3 Inhibitors
    Publication number: 20200331897
    Abstract: The present application provides detectable compounds useful for identifying compounds that bind (e.g., inhibit) MmpL3. Methods of identifying compounds that bind and/or inhibit MmpL3 are also provided.
    Type: Application
    Filed: February 21, 2020
    Publication date: October 22, 2020
    Applicants: Creighton University, Colorado State University Research Foundation
    Inventors: Jeffrey North, Amitkumar Navinchandra Pandya, Mary Jackson, Wei Li, Mercedes Gonzalez-Juarrero
  • Use of peptide-based inhibitors of the stat3-IL10 pathway for treating bacterial infection and granulomatous disease
    Patent number: 10512673
    Abstract: The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and Wegener's granulomatosis in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: December 24, 2019
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Colorado State University Research Foundation
    Inventors: Nadya I. Tarasova, Mercedes Gonzalez-Juarrero
  • USE OF PEPTIDE-BASED INHIBITORS OF THE STAT3-IL10 PATHWAY FOR TREATING BACTERIAL INFECTION AND GRANULOMATOUS DISEASE
    Publication number: 20180000901
    Abstract: The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and Wegener's granulomatosis in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal.
    Type: Application
    Filed: January 7, 2016
    Publication date: January 4, 2018
    Applicants: The United States of America, as represented by the Secretary, Department of Health & Human Servic, Colorado State University Research Foundation
    Inventors: Nadya I. Tarasova, Mercedes Gonzalez-Juarrero