Patents by Inventor Mercedes Segovia

Mercedes Segovia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods Of Treatment Of Inflammation Related Conditions Using Pluripotent Anti-inflammatory And Metabolic Modulators
    Publication number: 20220296546
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Application
    Filed: June 6, 2022
    Publication date: September 22, 2022
    Applicants: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPÚBLICA
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, Maria Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • IONIC CHANNEL MODULATION AS A METHOD FOR TREATING TUMORS THROUGH INFLAMMASOME ACTIVATION
    Publication number: 20220184004
    Abstract: The invention presents use of ion channel modulator to manipulate expression of the Tmem176b gene, also known as TORID (TOlerance Related and InduceD), to treat tumors.
    Type: Application
    Filed: October 28, 2021
    Publication date: June 16, 2022
    Inventors: Marcelo HILL MONGABURE, Sofia RUSSO ROSSI, Mercedes SEGOVIA DUARTE, María INÉS VARELA VEGA, Pablo OPPEZZO LLORENS
  • Immunoresponsive methods of treating tumors
    Patent number: 11246858
    Abstract: Within the scope of the present invention is a new pharmacological strategy for the treatment of tumors based on anti-tumoral immune responses.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: February 15, 2022
    Assignee: INSTITUT PASTEUR DE MONTEVIDEO
    Inventors: Marcelo Hill, Mercedes Segovia, Sofia Russo, Mathias Jeldres, Maria Romina Girotti, Maite Duhalde Vega, Yamil Damián Mahmoud
  • Methods for Treating Heart Transplant Rejection
    Publication number: 20200215083
    Abstract: Current therapeutic approach to treating heart allotransplantation rejection focus on immunosuppression protocols that carry harmful side effects after chronic use, which include global immune depression to the patient. The present inventors have discovered alternative and synergistic protocols based on inhibiting NF-?B and NLRP3 inflammasome-dependent IL-1?release with nitrated NSAID derivatives.
    Type: Application
    Filed: March 18, 2020
    Publication date: July 9, 2020
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Williams Arturo Porcal Quinta, Germán Adrian Galliussi López, Marcelo Hill, Mercedes Segovia
  • Methods of Treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic Modulators
    Publication number: 20200147017
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • Methods for treating heart transplant rejection
    Patent number: 10632132
    Abstract: Current therapeutic approach to treating heart allotransplantation rejection focus on immunosuppression protocols that carry harmful side effects after chronic use, which include global immune depression to the patient. The present inventors have discovered alternative and synergistic protocols based on inhibiting NF-?B and NLRP3 inflammasome-dependent IL-1? release with nitrated NSAID derivatives.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: April 28, 2020
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Williams Arturo Porcal Quinta, Germán Adrian Galliussi López, Marcelo Hill, Mercedes Segovia
  • Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
    Patent number: 10537537
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: January 21, 2020
    Assignees: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • Methods for Treating Heart Transplant Rejection
    Publication number: 20190255077
    Abstract: Current therapeutic approach to treating heart allotransplantation rejection focus on immunosuppression protocols that carry harmful side effects after chronic use, which include global immune depression to the patient. The present inventors have discovered alternative and synergistic protocols based on inhibiting NF-?B and NLRP3 inflammasome-dependent IL-1? release with nitrated NSAID derivatives.
    Type: Application
    Filed: January 24, 2019
    Publication date: August 22, 2019
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Williams Arturo Porcal Quinta, Germán Adrian Galliussi López, Marcelo Hill, Mercedes Segovia, Ignacio Anegón, Cristina Cuturi
  • Immunoresponsive Methods of Treating Tumors
    Publication number: 20180318273
    Abstract: Within the scope of the present invention is a new pharmacological strategy for the treatment of tumors based on anti-tumoral immune responses.
    Type: Application
    Filed: May 2, 2018
    Publication date: November 8, 2018
    Applicant: Institut Pasteur de Montevideo
    Inventors: Marcelo Hill, Mercedes Segovia, Sofia Russo, Maria Cristina Cuturi, Mathias Jeldres, Maria Romina Girotti, Maite Duhalde Vega, Yamil Damián Mahmoud
  • Methods of Treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic Modulators
    Publication number: 20180104202
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 16, 2017
    Publication date: April 19, 2018
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia