Abstract: Air purification and surface sterilization systems employing ultraviolet germicidal irradiation integratable in a discrete manner into indoor occupiable spaces in buildings. The systems may be used alone or in combination. The air purification system utilizes fan-powered disinfection units equipped with an ultraviolet light source operable to deactivate airborne pathogens. The surface sterilization system utilizes ultraviolet lamp units operable to deactivate surface accumulations of pathogen. Devices of either disinfection system may be integrated into ceiling or wall systems of the building interior space, or office furniture used in such spaces. The systems have applicability to institutional, commercial, and residential facilities as some examples.