Patents by Inventor Meritxell GALINDO CASAS

Meritxell GALINDO CASAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED POLYPEPTIDE CONJUGATES USING TRANSGLUTAMINASE
    Publication number: 20240009319
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Application
    Filed: July 5, 2023
    Publication date: January 11, 2024
    Applicant: RINAT NEUROSCIENCE CORP.
    Inventors: Santiago Esteban FARIAS, Meritxell GALINDO CASAS, Pavel STROP
  • MODIFIED CASPASE-9 POLYPEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20220235346
    Abstract: Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.
    Type: Application
    Filed: April 8, 2022
    Publication date: July 28, 2022
    Inventors: Meritxell GALINDO CASAS, Thomas John VAN BLARCOM
  • Modified caspase-9 polypeptides and methods of use thereof
    Patent number: 11326156
    Abstract: Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: May 10, 2022
    Assignee: ALLOGENE THERAPEUTICS, INC.
    Inventors: Meritxell Galindo Casas, Thomas John Van Blarcom
  • ENGINEERED POLYPEPTIDE CONJUGATES USING TRANSGLUTAMINASE
    Publication number: 20210162058
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Application
    Filed: October 14, 2020
    Publication date: June 3, 2021
    Applicant: RINAT NEUROSCIENCE CORP.
    Inventors: Santiago Esteban FARIAS, Meritxell GALINDO CASAS, Pavel STROP
  • Engineered polypeptide conjugates using transglutaminase
    Patent number: 10842881
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 24, 2020
    Assignee: Rinat Neuroscience Corp.
    Inventors: Santiago Esteban Farias, Meritxell Galindo Casas, Pavel Strop
  • ENGINEERED POLYPEPTIDE CONJUGATES USING TRANSGLUTAMINASE
    Publication number: 20190321482
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 24, 2019
    Applicant: RINAT NEUROSCIENCE CORP.
    Inventors: Santiago Esteban Farias, Meritxell Galindo Casas, Pavel Strop
  • MODIFIED CASPASE-9 POLYPEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20190127721
    Abstract: Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.
    Type: Application
    Filed: October 31, 2018
    Publication date: May 2, 2019
    Inventors: Meritxell GALINDO CASAS, Thomas John VAN BLARCOM
  • Engineered polypeptide conjugates using transglutaminase
    Patent number: 10195289
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: February 5, 2019
    Assignee: RINAT NEUROSCIENCE CORP.
    Inventors: Santiago Esteban Farias, Meritxell Galindo Casas, Pavel Strop
  • ENGINEERED POLYPEPTIDE CONJUGATES USING TRANSGLUTAMINASE
    Publication number: 20160193356
    Abstract: The present invention provides engineered polypeptide conjugates (e.g., antibody-drug-conjugates) comprising specific acyl donor glutamine-containing tags and amine donor agents. The invention also provides methods of making such engineered polypeptide conjugates using transglutaminase and methods of using thereof.
    Type: Application
    Filed: July 30, 2014
    Publication date: July 7, 2016
    Applicant: RINAT NEUROSCIENCE CORP.
    Inventors: Santiago Esteban FARIAS, Meritxell GALINDO CASAS, Pavel STROP