Patents by Inventor Merja E. Penttila

Merja E. Penttila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140335591
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 13, 2014
    Applicant: DANISCO US INC.
    Inventors: MERJA E. PENTTILA, MICHAEL WARD, HUAMING WANG, MARI J. VALKONEN, MARKKU L.A. SALOHEIMO
  • Patent number: 8753866
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: June 17, 2014
    Assignee: Danisco US Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku La Saloheimo
  • Publication number: 20100221775
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Application
    Filed: December 16, 2009
    Publication date: September 2, 2010
    Applicant: Genencor International, Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku L.A. Saloheimo
  • Patent number: 7662584
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: February 16, 2010
    Assignee: Danisco US Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku L. A. Saloheimo
  • Publication number: 20040186070
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Application
    Filed: September 15, 2003
    Publication date: September 23, 2004
    Applicant: Genencor International, Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku L.A. Saloheimo
  • Patent number: 6768001
    Abstract: The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those nucleic acid sequences, antibodies which bind to the xylanases of the present invention, methods for producing the xylanases of the present invention, and methods employing the xylanases of the present invention.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: July 27, 2004
    Assignee: Genencor International, Inc.
    Inventors: Markku L A Saloheimo, Matti Siika-Aho, Maija Tenkanen, Merja E. Penttila
  • Patent number: 6555335
    Abstract: The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those nucleic acid sequences, antibodies which bind to the xylanases of the present invention, methods for producing the xylanases of the present invention, and methods employing the xylanases of the present invention.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: April 29, 2003
    Assignee: Genencor International, Inc.
    Inventors: Markku La Saloheimo, Matti Siika-Aho, Maija Tenkanen, Merja E. Penttila
  • Publication number: 20030054518
    Abstract: The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those nucleic acid sequences, antibodies which bind to the xylanases of the present invention, methods for producing the xylanases of the present invention, and methods employing the xylanases of the present invention.
    Type: Application
    Filed: May 31, 2002
    Publication date: March 20, 2003
    Inventors: Markku La Saloheimo, Matti Siika-Aho, Maija Tenkanen, Merja E. Penttila
  • Publication number: 20010034045
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and lRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Application
    Filed: March 23, 2001
    Publication date: October 25, 2001
    Applicant: Genencor International, Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku L.A. Saloheimo
  • Patent number: 5108925
    Abstract: The present invention describes a shortened process for the production of beer, brewer's yeast strains having .alpha.-acetolactate decarboxylase activity (EC 4.1.1.5.), the method for the construction of such yeast strains and the recombinant DNA cloning vectors used. The method involves integrating the .alpha.-acetolactate decarboxylase gene into the ADC1 or PGK1 gene.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: April 28, 1992
    Assignee: Oy Panimolaboratorio - Bryggerilaboratorium AB
    Inventors: Tor-Magnus Enari, Matti J. Nikkola, Maija-Liisa A. Suthko, Merja E. Penttila, Paivi M. Lehtovaara-Helenius