Patents by Inventor Merle E. Olson

Merle E. Olson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10434210
    Abstract: The present invention is silver (I) periodate compounds and their use in preventing or reducing microbial contamination. The invention includes gels, coatings, and articles of manufacture having a surface contacted or coated with a gel comprising an antimicrobial silver (I) compound. Methods of treatment are also disclosed.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: October 8, 2019
    Assignee: INNOVOTECH, INC.
    Inventors: Merle E. Olson, Patricia L. Nadworny, Graeme Prosperi-Porta
  • Publication number: 20180168165
    Abstract: The present invention is compositions, methods of use, methods of treating, and articles of manufacture that include at least one silver iodate for imparting antimicrobial properties, particularly as it relates to the manufacture, use, and properties of medical devices. The invention also includes obtaining and using one or more silver iodate reaction products from a diperiodatoargentate, wherein the reaction products are obtained using a hydrothermal reaction.
    Type: Application
    Filed: February 17, 2018
    Publication date: June 21, 2018
    Inventors: Merle E. Olson, Justin J. Anderson, Patricia L. Nadworny, Amin M. Omar
  • Patent number: 9723843
    Abstract: The present invention is silver (I) periodate compounds and their use in preventing or reducing microbial contamination. The invention includes coatings and articles of manufacture having a surface containing an anti-microbial silver (I) compound. Methods of treatment are also disclosed.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: August 8, 2017
    Assignee: INNOVOTECH INC.
    Inventors: Merle E. Olson, Patricia Nadworny, Amin M Omar, Yanira E Cabrera
  • Publication number: 20160135469
    Abstract: The present invention is silver (I) periodate compounds and their use in preventing or reducing microbial contamination. The invention includes coatings and articles of manufacture having a surface containing an anti-microbial silver (I) compound. Methods of treatment are also disclosed.
    Type: Application
    Filed: January 21, 2016
    Publication date: May 19, 2016
    Inventors: Merle E. Olson, Patricia Nadworny, Amin M. Omar, Yanira E. Cabrera
  • Publication number: 20160106107
    Abstract: The invention is a method and composition for treating biofilm using a high valency silver ion.
    Type: Application
    Filed: June 22, 2007
    Publication date: April 21, 2016
    Inventors: Lyriam L. Marques, Merle E. Olson, Michael W. Harding
  • Publication number: 20150224220
    Abstract: The present invention is silver (I) periodate compounds and their use in preventing or reducing microbial contamination. The invention includes gels, coatings, and articles of manufacture having a surface contacted or coated with a gel comprising an antimicrobial silver (I) compound. Methods of treatment are also disclosed.
    Type: Application
    Filed: July 19, 2013
    Publication date: August 13, 2015
    Inventors: Merle E. Olson, Patricia Nadworny, Graeme Prosperi-Porta
  • Publication number: 20140328890
    Abstract: The present invention is compositions, methods of use, methods of treating, and articles of manufacture that include at least one silver iodate for imparting antimicrobial properties, particularly as it relates to the manufacture, use, and properties of medical devices. The invention also includes obtaining and using one or more silver iodate reaction products from a diperiodatoargentate, wherein the reaction products are obtained using a hydrothermal reaction.
    Type: Application
    Filed: March 26, 2014
    Publication date: November 6, 2014
    Inventors: Merle E. Olson, Justin J. Anderson, Patricia L. Nadworny, Amin M. Omar
  • Publication number: 20140328887
    Abstract: The present application discloses a method of making a surface antimicrobial by coating or forming a surface with a silver (I) periodate as well as articles of manufacture comprising a silver (I) periodate. The present application also discloses a method of preventing or reducing microbial contamination on a substrate by coating the substrate with at least one silver (I) periodate. The substrate can be a wound dressing, a medical instrument, a medical device, a metallic article, a plant or a seed.
    Type: Application
    Filed: August 22, 2012
    Publication date: November 6, 2014
    Applicant: Innovotech, Inc.
    Inventors: Merle E. Olson, Patricia Nadworny, Amin M. Omar, Yanira E. Cabrera
  • Publication number: 20120328713
    Abstract: The invention pertains to methods and compositions for preventing or reducing microbial contamination using a silver (III) periodate as antimicrobial active hi a preferred embodiment the silver (III) periodate is used in a coating upon a medical device or implant to confer coating uniformity and antimicrobial efficacy. Also provided is a method of synthetising a silver (III) periodate in high yield by heating a source of single valency silver ions in water and subsequently combining it with a heated solution comprising persulfate, a by droxide, and a periodate.
    Type: Application
    Filed: December 14, 2010
    Publication date: December 27, 2012
    Inventors: Merle E Olson, Nick Allan, Amin Mousa Omar, Justin J Anderson, Patricia L Nadworny, Michael W Harding
  • Publication number: 20120329675
    Abstract: This invention is an apparatus and method for susceptibility testing one or more biofilms, for selecting one or more anti-microbial combinations with efficacy against the biofilm, and/or in treating a disease or condition mediated by the biofilm The invention includes methods for the selection of antibiotic combinations with efficacy against a specific microbial type and for the formulation of microbe-specific test plates. The invention also includes an assay system to test patient specific isolates for sensitivity to the anti-microbial combinations.
    Type: Application
    Filed: July 20, 2010
    Publication date: December 27, 2012
    Inventors: Merle E. Olson, Howard Ceri
  • Publication number: 20120219638
    Abstract: The present invention includes antimicrobial silver-containing compositions that are effective in treating Erwinia species bacteria. These compositions are particularly effective for treating plants susceptible to Erwinia species infections.
    Type: Application
    Filed: November 21, 2011
    Publication date: August 30, 2012
    Inventors: Merle E. Olson, Michael W. Harding
  • Publication number: 20120058169
    Abstract: The present invention is compositions, methods of use, methods of treating, and articles of manufacture that include at least one silver iodate for imparting antimicrobial properties, particularly as it relates to the manufacture, use, and properties of medical devices. The invention also includes obtaining and using one or more silver iodate reaction products from a diperiodatoargentate, wherein the reaction products are obtained using a hydrothermal reaction.
    Type: Application
    Filed: August 22, 2011
    Publication date: March 8, 2012
    Inventors: Merle E. Olson, Justin J. Anderson, Patricia L. Nadworny, Amin M. Omar
  • Publication number: 20110275518
    Abstract: The present invention is compositions and methods for improving seed germination rates or speed using a composition comprising at least one high valency silver ion. The compositions and methods of the present invention are effective in treating biofilms.
    Type: Application
    Filed: June 9, 2008
    Publication date: November 10, 2011
    Inventors: Lyriam L. Marques, Merle E. Olson, Michael W. Harding
  • Publication number: 20110250290
    Abstract: The invention is a method and composition for treating biofilm using a silver deposition compound. In preferred embodiments of the invention, the anti-biofilm agent is used to preserve or disinfect plant material, including seeds, leaves, stems, vessels, flowers, roots and fruits.
    Type: Application
    Filed: January 14, 2011
    Publication date: October 13, 2011
    Inventors: Lyriam L. Marques, Merle E. Olson, Michael W. Harding
  • Publication number: 20110245171
    Abstract: The invention comprises 1) an oral composition, including an oral rehydration composition or solution, comprising an effective amount of a compound selected from epidermal growth factor (EGF) and agonists to the epidermal growth factor receptor, 2) a kit comprising an oral rehydration composition containing an effective amount of a compound selected from epidermal growth factor and agonists to the epidermal growth factor receptor, and 3) methods for the treatment and prevention of dehydration and diarrhea, and enhancing intestinal healing, reducing bacterial colonization, reducing the incidence of weight loss, increasing food uptake, enhancing rehydration, and enhancing mucosal healing in an animal having diarrhea.
    Type: Application
    Filed: September 29, 2005
    Publication date: October 6, 2011
    Inventors: James A. Hardin, Merle E. Olson, D. Grant Gall, Loretta Gall, Andre G. Buret
  • Publication number: 20100266716
    Abstract: The present invention is safe photodynamic agents and their use in treating microbial contamination.
    Type: Application
    Filed: October 27, 2008
    Publication date: October 21, 2010
    Inventors: Merle E. Olson, Nicholas D. Allan
  • Publication number: 20100129466
    Abstract: The invention is a method and composition for treating biofilm using a high valency silver ion.
    Type: Application
    Filed: June 22, 2007
    Publication date: May 27, 2010
    Applicant: INOVOTECH, INC.
    Inventors: Lyriam L. Marques, Merle E. Olson, Michael W. Harding
  • Publication number: 20080318269
    Abstract: This invention is a diagnostic plate that can be used to select antibiotic combinations with efficacy against microorganisms growing as a biofilm. The plate allows growth of biofilm on a plurality of projections, and the subsequent simultaneous challenge of biofilms on all projections of the plate to independent concentrations and combinations of anti-biofilm agents. Resistance of microorganisms to antibiotics is higher when they grow as a biofilm, as compared to when they grow in a planktonic state which is usually used to determine their level of antibiotic sensitivity. Growth of microorganims that slough off the biofilm in the anti-biofilm agent challenge determines the Minimum Inhibitory Concentration (MIC) which relates to sensitivity of the microorganisms in a planktonic state. Growth of any surviving microorganims from the biofilm in a subsequent recovery step determines the Minimal Biofilm Eradication Concentration (MBEC) which relates to the sensitivity of the microorganisms growing as a biofilm.
    Type: Application
    Filed: July 22, 2006
    Publication date: December 25, 2008
    Inventors: Merle E Olson, Howard Ceri
  • Publication number: 20080318268
    Abstract: This invention is a diagnostic plate that can be used to select antibiotic combinations with efficacy against microorganisms growing as a biofilm. The plate allows growth of biofilm on a plurality of projections, and the subsequent simultaneous challenge of biofilms on all projections of the plate to independent concentrations and combinations of anti-biofilm agents. Resistance of microorganisms to antibiotics is higher when they grow as a biofilm, as compared to when they grow in a planktonic state which is usually used to determine their level of antibiotic sensitivity. Growth of microorganisms that slough off the biofilm in the anti-biofilm agent challenge determines the Minimum Inhibitory Concentration (MIC) which relates to sensitivity of the microorganisms in a planktonic state. Growth of any surviving microorganisms from the biofilm in a subsequent recovery step determines the Minimal Biofilm Eradication Concentration (MBEC) which relates to the sensitivity of the microorganisms growing as a biofilm.
    Type: Application
    Filed: January 22, 2006
    Publication date: December 25, 2008
    Inventors: Merle E Olson, Howard Ceri
  • Publication number: 20040265313
    Abstract: This invention relates to methods and compositions to regulate biofilm formation. In particular, the invention relates to regulation of biofilm formation by modulating the GacA/GacS regulatory system.
    Type: Application
    Filed: April 21, 2004
    Publication date: December 30, 2004
    Applicant: University Technologies International, Inc.
    Inventors: Douglas G. Storey, Michael D. Parkins, Howard Ceri, Merle E. Olson