Patents by Inventor Merritt Edlind

Merritt Edlind has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF TRANSLATIONAL PROFILING TO IDENTIFY TARGET MOLECULES FOR THERAPEUTIC TREATMENT
    Publication number: 20190136321
    Abstract: The present invention provides methods of identifying an agent or drug candidate molecule, validating a target, and identifying normalizing therapeutics that modulates translation, such as in an oncogenic signaling pathway, in a biological sample as determined by translational profiling of one or more genes in the biological sample. The present invention also provides diagnostic and therapeutic methods using the translational profiling methods described herein.
    Type: Application
    Filed: October 15, 2018
    Publication date: May 9, 2019
    Inventors: Davide Ruggero, Andrew Hsieh, Merritt Edlind, Kevan M. Shokat, James Appleman, Steve Worland
  • USE OF TRANSLATIONAL PROFILING TO IDENTIFY TARGET MOLECULES FOR THERAPEUTIC TREATMENT
    Publication number: 20190093170
    Abstract: The present invention provides methods of identifying an agent that modulates an oncogenic signaling pathway in a biological sample by generating a translational profile of gene translational levels in the biological sample. The present invention also provides diagnostic and therapeutic methods using the translational profiling methods described herein.
    Type: Application
    Filed: October 12, 2018
    Publication date: March 28, 2019
    Inventors: Davide RUGGERO, Andrew HSIEH, Merritt EDLIND
  • USE OF TRANSLATIONAL PROFILING TO IDENTIFY TARGET MOLECULES FOR THERAPEUTIC TREATMENT
    Publication number: 20140288097
    Abstract: The present invention provides methods of identifying an agent or drug candidate molecule, validating a target, and identifying normalizing therapeutics that modulates translation, such as in an oncogenic signaling pathway, in a biological sample as determined by translational profiling of one or more genes in the biological sample. The present invention also provides diagnostic and therapeutic methods using the translational profiling methods described herein.
    Type: Application
    Filed: February 7, 2014
    Publication date: September 25, 2014
    Applicant: The Regents of The University of California
    Inventors: Davide Ruggero, Andrew Hsieh, Merritt Edlind, Kevan M. Shokat, James Appleman, Steve Worland
  • USE OF TRANSLATIONAL PROFILING TO IDENTIFY TARGET MOLECULES FOR THERAPEUTIC TREATMENT
    Publication number: 20140243356
    Abstract: The present invention provides methods of identifying an agent that modulates an oncogenic signaling pathway in a biological sample by generating a translational profile of gene translational levels in the biological sample. The present invention also provides diagnostic and therapeutic methods using the translational profiling methods described herein.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 28, 2014
    Applicant: The Regents of the University of California
    Inventors: Davide Ruggero, Andrew Hsieh, Merritt Edlind