Patents by Inventor Merve ZUVIN

Merve ZUVIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC NANOPARTICLES CONTAINING ARGONAUTE FOR MICRORNA DELIVERY AND COMPOSITIONS AND METHODS USING SAME
    Publication number: 20210023239
    Abstract: The present invention relates to oligonucleotide carriers for oligonucleotide delivery to a subject to provide gene therapy. More particularly, the present invention relates to therapeutic nanoparticles for microRNA (miRNA) delivery to a subject. More particularly, the present invention relates to therapeutic nanoparticles wherein miRNA is bindable to biocompatible nanoparticles using natural gene carrier Argonaute (AGO) protein or a variant thereof. Optionally, therapeutic nanoparticles of the present invention additionally contain targeting moieties for targeting therapeutic nanoparticles to cancer cells and/or chemotherapeutic agents. Optionally, biocompatible nanoparticles are trackable nanoparticles, such as superparamagnetic iron oxide nanoparticles (SPION), to provide multifunctional theranostics.
    Type: Application
    Filed: March 10, 2018
    Publication date: January 28, 2021
    Applicants: KOC UNIVERSITESI, SABANCI UNIVERSITESI, SABANCI UNIVERSITESI NANOTEKNOLOJI ARASTIRMA VE UYGULAMA MERKEZI
    Inventors: Havva Yagci ACAR, Devrim GOZUACIK, Ali KOSAR, Ozlem UNAL, Muhammed KOCAK, Yunus AKKOC, Merve ZUVIN