Patents by Inventor Mervyn DeSouza

Mervyn DeSouza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of producing methionine
    Patent number: 9493801
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: November 15, 2016
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Brian Brazeau, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Riera, Yong-Uk Shin, Hyewon Um
  • Compositions and Methods of Producing Methionine
    Publication number: 20160024541
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Application
    Filed: August 6, 2015
    Publication date: January 28, 2016
    Inventors: Brian BRAZEAU, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Riera, Yong-Uk Shin, Hyewon Um
  • Compositions and methods of producing methionine
    Patent number: 9150893
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 6, 2015
    Assignee: CJ Cheiljedang Corporation
    Inventors: Brian Brazeau, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Riera, Yong-Uk Shin, Hyewon Um
  • Compositions and methods of producing methionine
    Patent number: 8551742
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: October 8, 2013
    Assignee: CJ Cheiljedang Corporation
    Inventors: Brian Brazeau, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Riera, Yong-Uk Shin, Hyewon Um
  • Compositions and Methods of Producing Methionine
    Publication number: 20130260424
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 3, 2013
    Applicant: CJ Cheiljedang Corporation
    Inventors: Brian BRAZEAU, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Reira, Yong-Uk Shin, Hyewon Um
  • Compositions and Methods of Producing Methionine
    Publication number: 20110183383
    Abstract: Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
    Type: Application
    Filed: April 11, 2007
    Publication date: July 28, 2011
    Applicant: CJ Cheijedang Corporation
    Inventors: Brian Brazeau, Jin-Sook Chang, Kwang Myung Cho, Young Wook Cho, Mervyn Desouza, Holly J. Jessen, So-Young Kim, Wei Niu, Fernando A. Sanchez-Riera, Yong-Uk Shin, Hyewon Um
  • Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
    Patent number: 7582455
    Abstract: Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: September 1, 2009
    Assignee: Cargill, Incorporated
    Inventors: Brian J. Brazeau, Ellen Burke, Mervyn DeSouza, Steven J. Gort, Paula M. Hicks, Sherry R. Kollmann, Peter Luginbuhl, Sara C. McFarlan, Toby Richardson, Fernando A. Sanchez-Riera, Christopher Solheid, David Weiner, Lishan Zhao
  • Products and Methods for In Vivo Secretion of Monatin
    Publication number: 20070105938
    Abstract: Products and methods for the in vivo production of monatin sweetener are provided. The products include microorganisms that are genetically modified to secrete or to improve secretion of monatin; microorganisms that are genetically modified to produce monatin; and microorganisms that are genetically modified to both secrete or improve secretion of monatin and produce monatin. The methods include producing monatin in such genetically engineered microorganisms.
    Type: Application
    Filed: April 20, 2006
    Publication date: May 10, 2007
    Applicant: Cargill, Incorporated
    Inventors: James Anderson, Mervyn DeSouza, Paula Hicks, Sherry Kollmann, Jose Laplaza
  • Products and methods for in vivo secretion of monatin
    Publication number: 20070099277
    Abstract: Products and methods for the in vivo production of monatin sweetener are provided. The products include microorganisms that are genetically modified to secrete or to improve secretion of monatin; microorganisms that are genetically modified to produce monatin; and microorganisms that are genetically modified to both secrete or improve secretion of monatin and produce monatin. The methods include producing monatin in such genetically engineered microorganisms.
    Type: Application
    Filed: October 10, 2006
    Publication date: May 3, 2007
    Applicant: Cargill, Incorporated
    Inventors: James Anderson, Mervyn DeSouza, Paula Hicks, Sherry Kollmann
  • Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
    Publication number: 20060252135
    Abstract: Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
    Type: Application
    Filed: April 26, 2006
    Publication date: November 9, 2006
    Applicant: Cargill, Incorporated
    Inventors: Brian Brazeau, Ellen Burke, Mervyn DeSouza, Steven Gort, Paula Hicks, Sherry Kollmann, Peter Luginbuhl, Sara McFarlan, Toby Richardson, Fernando Sanchez-Riera, Christopher Solheid, David Weiner, Lishan Zhao
  • Carotenoid biosynthesis
    Publication number: 20050260699
    Abstract: The invention provides materials and methods that can be used to make carotenoids having greater than 40 carbon atoms (C>40). The invention also provides isolated nucleic acid molecules that encode polypeptides that allow C40 carotenoids to be converted to C50 carotenoids. The isolated nucleic acid molecules can be introduced into production cells, wherein the production cell becomes capable of the biosynthesis and the conversion of the C>40 carotenoids.
    Type: Application
    Filed: November 21, 2001
    Publication date: November 24, 2005
    Inventors: Mervyn Desouza, Holly Jessen, William Schroeder, Ravi Gokarn
  • Production of monatin and monatin precursors
    Publication number: 20050221455
    Abstract: Methods and compositions that can be used to make monatin or salt thereof from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
    Type: Application
    Filed: October 21, 2004
    Publication date: October 6, 2005
    Inventors: Sara McFarlan, Paula Hicks, Mary Zidwick, Fernando Sanchez-Riera, Douglas Cameron, Mervyn deSouza, John Rosazza, Steven Gort, Timothy Abraham
  • Carotenoid biosynthesis
    Publication number: 20050003474
    Abstract: Membranous bacteria that produce astaxanthin and other carotenoids are described, as well as isolated nucleic acids and expression vectors that can be used for producing carotenoids in microorganisms.
    Type: Application
    Filed: May 18, 2004
    Publication date: January 6, 2005
    Inventors: Mervyn Desouza, Sherry Kollmann