Patents by Inventor Mervyn Merrilees

Mervyn Merrilees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for promoting elastogenesis and elastin fiber formation by increasing tropoelastin expression
    Patent number: 8367619
    Abstract: Compositions and methods are provided for promoting elastin fiber formation (elastogenesis) in a cell, including methods that comprise contacting a cell that is capable of elastogenesis with (i) a mutated biglycan polypeptide that lacks chondroitin sulphate proteoglycan chains, (ii) a versican V3 isoform polypeptide that lacks most or all of the polypeptide regions encoded by one or more of exons 4, 5 or 6 or by exons 9-10 or 11-13, and/or with (iii) metastatin.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: February 5, 2013
    Assignee: Benaroya Research Institute at Virginia Mason
    Inventors: Thomas N. Wight, Mervyn Merrilees
  • Therapeutic compounds and methods
    Patent number: 7816335
    Abstract: Therapeutic agents and methods useful to modulate the activity of V3.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: October 19, 2010
    Inventors: Thomas N. Wight, Mervyn Merrilees
  • COMPOSITIONS AND METHODS FOR ALTERING ELASTOGENESIS
    Publication number: 20100197563
    Abstract: Compositions and methods are provided for promoting elastin fiber formation (elastogenesis) in a cell, including methods that comprise contacting a cell that is capable of elastogenesis with (i) a mutated biglycan polypeptide that lacks chondroitin sulphate proteoglycan chains, (ii) a versican V3 isoform polypeptide that lacks most or all of the polypeptide regions encoded by one or more of exons 4, 5 or 6 or by exons 9-10 or 11-13, and/or with (iii) metastatin.
    Type: Application
    Filed: February 7, 2008
    Publication date: August 5, 2010
    Inventors: Thomas N. Wight, Mervyn Merrilees
  • Therapeutic compounds and methods
    Publication number: 20040213762
    Abstract: Therapeutic agents and methods useful to modulate the activity of V3.
    Type: Application
    Filed: October 11, 2002
    Publication date: October 28, 2004
    Inventors: Thomas N. Wight, Mervyn Merrilees