Patents by Inventor Mesfin Gewe

Mesfin Gewe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARTHROSPIRA PLATENSIS NON-PARENTERAL THERAPEUTIC DELIVERY PLATFORM
    Publication number: 20260109941
    Abstract: The present disclosure provides non-parenteral compositions comprising a recombinant Spirulina comprising at least one exogenous therapeutic. Compositions of the present disclosure can be used as vaccines and/or therapeutic drugs. The present disclosure also provides methods of making recombinant Spirulina comprising at least one exogenous therapeutic, and methods of treatment.
    Type: Application
    Filed: August 20, 2025
    Publication date: April 23, 2026
    Inventors: James ROBERTS, Michael TASCH, Mesfin GEWE, Benjamin JESTER, Tracy SAVERIA
  • Arthrospira platensis non-parenteral therapeutic delivery platform
    Patent number: 12503682
    Abstract: The present disclosure provides non-parenteral compositions comprising a recombinant Spirulina comprising at least one exogenous therapeutic. Compositions of the present disclosure can be used as vaccines and/or therapeutic drugs. The present disclosure also provides methods of making recombinant Spirulina comprising at least one exogenous therapeutic, and methods of treatment.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: December 23, 2025
    Assignee: Lumen Bioscience, Inc.
    Inventors: James Roberts, Michael Tasch, Mesfin Gewe, Benjamin Jester, Tracy Saveria
  • ARTHROSPIRA PLATENSIS NON-PARENTERAL THERAPEUTIC DELIVERY PLATFORM
    Publication number: 20210338751
    Abstract: The present disclosure provides non-parenteral compositions comprising a recombinant Spirulina comprising at least one exogenous therapeutic. Compositions of the present disclosure can be used as vaccines and/or therapeutic drugs. The present disclosure also provides methods of making recombinant Spirulina comprising at least one exogenous therapeutic, and methods of treatment.
    Type: Application
    Filed: May 3, 2021
    Publication date: November 4, 2021
    Inventors: James ROBERTS, Michael TASCH, Mesfin GEWE, Benjamin JESTER, Tracy SAVERIA
  • NKG2D decoys
    Patent number: 10815290
    Abstract: Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands; (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions; and (iii) potentiate an immune response against a vaccine as well as many other potential uses.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 27, 2020
    Assignee: FRED HUTCHINSON CANCER RESEARCH CENTER
    Inventors: Mesfin Gewe, Roland K. Strong, Martin Prlic, Peter Rupert, Thomas Spies, Veronika Spies
  • NKG2D DECOYS
    Publication number: 20180371051
    Abstract: Single chain, multimerized, and/or glycosylated NKG2D decoys are described. The NKG2D decoys have high affinity and avidity for surface bound and soluble NKG2D ligands and can be used to (i) identify NKG2D ligands; (ii) treat cancer, graft vs. host disease (GVHD), and inflammatory conditions; and (iii) potentiate an immune response against a vaccine as well as many other potential uses.
    Type: Application
    Filed: November 10, 2016
    Publication date: December 27, 2018
    Applicant: Fred Hutchinson Cancer Research Center
    Inventors: Roland K. Strong, Mesfin Gewe, Martin Prlic, Peter Rupert, Thomas Spies, Veronika Spies