Abstract: Provided are a pole piece, a core, and a cell. The cell includes the pole piece. The pole piece includes a pole piece body and tabs. Multiple tabs are disposed on an edge of the pole piece body and at intervals in a first direction. A notch is formed at the end of each tab facing away from the pole piece body.

Abstract: A dendritic cell cancer vaccine obtained by activating dendritic cells in vitro with delivery particles loaded with cell components is provided, wherein the delivery particles are nanoparticles and/or micronparticles, the cell components are derived from water-soluble components and/or non-water-soluble components of cancer cells and/or tumor tissues, the activating is co-incubating the delivery particles loaded with the cell components with the dendritic cells.

Abstract: A targeting delivery system loaded with whole-cell components, which relates to the technical field of immunotherapy. The targeting delivery system is a nano-sized or micron-sized particle with a target head on the surface, and the particle is loaded with whole-cell components of cancer cells or cancer tissues; the whole-cell components are water-soluble ingredients and water-insoluble ingredients of whole cells in cells or tissues, and the water-insoluble ingredients are dissolved by a solubilizer; and the target head binds to a molecule on the surface of a specific cell or tissue, so as to help the particle to enter the cell or tissue. According to the targeting delivery system, a specific solubilizer is used to solubilize the water-insoluble part, which allows same to be dissolved in an aqueous solution, so that the whole-cell antigens of the water-soluble ingredients and the water-insoluble ingredients in cancer cells or tissues can be combined to prepare a cancer vaccine.

Abstract: A detection method for tumor-specific T cells includes: collecting whole-cell components of tumor cells or tumor tissues, using free whole-cell components or loading whole-cell lysate components on nano/micron particles, then performing co-incubating with peripheral immune cells, and after the cancer-specific T cells are activated, detecting specific molecules of the tumor-specific T cells, so that the content of the cancer-specific T cells in peripheral tissues such as peripheral blood can be determined. The whole-cell lysate components in the present invention are water-soluble components and non-water-soluble components, and are in a free state or are loaded on nano particles or micron particles. The loading mode is that: the whole-cell water-soluble components and non-water-soluble components are respectively or simultaneously encapsulated inside the particles, and/or respectively or simultaneously loaded on the surfaces of the particles.

Abstract: A delivery system for delivering water-soluble components and water-insoluble components of whole-cell components using nano-sized or micro-sized particles, and a use of which in preparing vaccines for preventing and treating cancer. The whole-cell components delivery system consisting of a nano-sized or micron-sized particle and whole-cell components loaded on the particle, the whole-cell components are water-soluble components and water-insoluble components of a whole cell in a cell or tissue. The mutated proteins or peptides produced by cancer in cellular components are loaded on nanoparticles or micronparticles. These immunogenic substances generated by mutations in disease in whole-cell components can be used for cancer prevention and treatment and preparing vaccines for preventing and/or treating cancer.