Abstract: The present disclosure relates to an antibody binding specifically to tryptophanyl-tRNA synthetase (WARS) or a fragment thereof. The antibody or the fragment thereof of the present disclosure has an excellent ability to bind specifically to WARS with no cross-reactivity with other ARSs and has an excellent ability to detect WARS and inhibit the activity thereof. Therefore, it can be effectively used for diagnosing and/or treating an infectious disease.

Abstract: The present disclosure relates to a method for determining the mortality risk of an infectious inflammatory disease on the basis of the concentrations of tryptophanyl-tRNA synthetase (WARS) and cytokines. The method for determining the mortality risk of the present disclosure can effectively identify patients who are at high risk of mortality due to an infectious inflammatory disease within a short period of time and, as such, can be very helpful for performing timely therapy.

Abstract: The present invention relates to a use of a crude extract, non-polar solvent soluble extract or purified extract of the hardy kiwifruit for the preparation of therapeutic agent for treating and preventing baldness disorder and seborrheic skin disease in human and mammal, and health care food, food additives, feed additives, cosmetic composition comprising the same. The hardy kiwifruit reduced blood DHT level, promoted the formation of hair root in mouse model experiment, and inhibited the falling out of hair and improved seborrheic skin disease of volunteers such as keratigenous skin, seborrhea etc.

Abstract: The present invention relates to a use of a crude extract, non-polar solvent soluble extract or purified extract of the hardy kiwifruit for the preparation of therapeutic agent for treating and preventing baldness disorder and seborrheic skin disease in human and mammal, and health care food, food additives, feed additives, cosmetic composition comprising the same. The hardy kiwifruit reduced blood DHT level, promoted the formation of hair root in mouse model experiment, and inhibited the falling out of hair and improved seborrheic skin disease of volunteers such as keratigenous skin, seborrhea etc.

Abstract: The present invention relates to a use of a crude extract, non-polar solvent soluble extract or purified extract of the hardy kiwifruit for the preparation of therapeutic agent for treating and preventing baldness disorder and seborrheic skin disease in human and mammal, and health care food, food additives, feed additives, cosmetic composition comprising the same. The hardy kiwifruit reduced blood DHT level, promoted the formation of hair root in mouse model experiment, and inhibited the failing out of hair and improved seborrheic skin disease of volunteers such as keratigenous skin, seborrhea etc.

Abstract: The present invention provides a pharmaceutical composition comprising the extract of hardy kiwifruit as an active ingredient in an effective amount to treat and prevent allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum and reducing the level of Th2 cytokines and IgE in serum. The present invention also provides a use of above extract for the preparation of pharmaceutical composition. The present invention also provides a health food or food additives, a cosmetic composition, a feed or feed additives comprising above extract for prevention or alleviation of allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum, and reducing the level of Th2 cytokines and IgE in serum.

Abstract: The present invention is related to a crude drug composition essentially comprising herbs of Sinapis Semen Alba, Ginseng Radix, Zingiberis Rhizoma Siccus, Amomi Fructus, Myristicae Semen, Saussureae Radix, Cyperi Rhizoma, Magnoliae Cortex, Arecae Semen, Crataegi Fructus, Atractylodes Rhizoma Alba, Agastachis Herba, Glycyrrhiza Radix and additionally comprising at least one herb selected from group consisting of Polygonati Rhizoma, Artemisiae Argyi Folium, Forsythiae Fructus, Caryophylli Flos, Raphani Semen, Menthae Herba according to the need for the prevention and treatment of gastrointestinal dyskinetic diseases and methods of using the above crude drug composition and pharmaceutical composition as prokinetic agent.

Abstract: The present invention is related to pharmaceutical composition essentially comprising herbal extract of Chaenomelis Fructus, Achyranthis Radix, Acanthopanax, Phlomidis Radix, Gentianae Radix, Clematidis Radix, and additionally comprising herbal extract selected from group consisting of Angelicae Radix, Cnidii Rhizoma, Gastrodiae Rhizoma, Safflower, Cinnamomi Cortex, Job's tear, Aurantii nobilis Pericapium, Ledebouriellae Radix, Lonicera japonica, Akebiae caulis, Caragana chamlagu, Licorice root, Notopterygium incisum, Persicae semen, Eucommia ulmoides, Atractylodes Rhizoma, Torilis japonica according to the need for the prevention and treatment of arthritic diseases and methods of using the above extracts and composition as potent anti-inflammatory and anti-arthritic agents.

Abstract: The present invention is related to pharmaceutical composition comprising an extract of Lentinus lepideus prepared by inventive preparation showing immune enhancing and immune modulating activity.

Abstract: The present invention is related to a crude drug composition essentially comprising herbs of Sinapis Semen Alba, Ginseng Radix, Zingiberis Rhizoma Siccus, Amomi Fructus, Myristicae Semen, Saussureae Radix, Cyperi Rhizoma, Magnoliae Cortex, Arecae Semen, Crataegi Fructus, Atractylodes Rhizoma Alba, Agastachis Herba, Glycyrrhiza Radix and additionally comprising at least one herb selected from group consisting of Polygonati Rhizoma, Artemisiae Argyi Folium, Forsythiae Fructus, Caryophylli Flos, Raphani Semen, Menthae Herba according to the need for the prevention and treatment of gastrointestinal dyskinetic diseases and methods of using the above crude drug composition and pharmaceutical composition as prokinetic agent.

Abstract: The present invention is related to pharmaceutical composition essentially comprising herbal extract of Chaenomelis Fructus, Achyranthis Radix, Acanthopanax, Phlomidis Radix, Gentianae Radix, Clematidis Radix, and additionally comprising herbal extract selected from group consisting of Angelicae Radix, Cnidii Rhizoma, Gastrodiae Rhizoma, Safflower, Cinnamomi Cortex, Job's tear, Aurantii nobilis Pericapium, Ledebouriellae Radix, Lonicera japonica, Akebiae caulis, Caragana chamlagu, Licorice root, Notopterygium incisum, Persicae semen, Eucommia ulmoides, Atractylodes Rhizoma, Torilis japonica according to the need for the prevention and treatment of arthritic diseases and methods of using the above extracts and composition as potent anti-inflammatory and anti-arthritic agents.