Abstract: The present invention relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The Corynebacterium glutamicum mutant strain is able to produce L-lysine in an improved yield as a result of increasing the supply of the L-lysine precursor and sugar utilization by increasing or enhancing the expression of the gene encoding enolase and/or reducing or weakening the expression of the gluconate operon transcriptional repressor.

Abstract: The present disclosure relates to a Corynebacterium sp. mutant strain having increased L-arginine or L-citrulline productivity and a method of producing L-arginine or L-citrulline using the same. The Corynebacterium sp. mutant strain has enhanced activity of acetylglutamate kinase involved in the L-arginine biosynthesis pathway, and thus is capable of producing L-arginine or L-citrulline in an increased yield compared to a parent strain.

Abstract: The present disclosure relates to a Corynebacterium sp. mutant strain having increased L-arginine or L-citrulline productivity and a method of producing L-arginine or L-citrulline using the same. The Corynebacterium sp. mutant strain has enhanced activity of acetylornithine aminotransferase involved in the L-arginine biosynthesis pathway, and thus is capable of producing L-arginine or L-citrulline productivity in an increased yield compared to a parent strain.

Abstract: The present disclosure relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The Corynebacterium glutamicum mutant strain may produce L-lysine in an improved yield by inhibiting the conversion of oxaloacetate to citrate due to decreased or inhibited expression of the gene encoding the citrate synthase.

Abstract: The present invention relates to a pharmaceutical composition for treating inflammatory disease containing a peptide derived from Octopus minor. The novel antibacterial peptide or fragment thereof according to the present invention may efficiently inhibit pro-inflammatory cytokines and chemokines responsible for inflammatory responses in LPS-activated macrophages, and thus may be effectively used to prevent or treat inflammatory disease.

Abstract: According to an embodiment, a method for automatically providing a cryptocurrency to a recommender using social networking service (SNS) propagation comprises a recommending step in which a blockchain membership node of a member having membership in a proof-of-expansion (PoX) blockchain platform server recommends an identity (ID) of an SNS friend of the member to the PoX blockchain platform server, a registering step in which the PoX blockchain platform server newly registers the ID of the SNS friend as a blockchain membership node, and a reward rate determining step in which the PoX blockchain platform server determines a reward rate for each blockchain member in association with the number of SNS friend IDs that the blockchain member recommends.

Abstract: According to an embodiment, a method for automatically providing a cryptocurrency to a recommender using social networking service (SNS) propagation comprises a recommending step in which a blockchain membership node of a member having membership in a proof-of-expansion (PoX) blockchain platform server recommends an identity (ID) of an SNS friend of the member to the PoX blockchain platform server, a registering step in which the PoX blockchain platform server newly registers the ID of the SNS friend as a blockchain membership node, and a reward rate determining step in which the PoX blockchain platform server determines a reward rate for each blockchain member in association with the number of SNS friend IDs that the blockchain member recommends.

Abstract: According to an embodiment, a method for automatically providing a cryptocurrency to a recommender using social networking service (SNS) propagation comprises a recommending step in which a blockchain membership node of a member having membership in a proof-of-expansion (PoX) blockchain platform server recommends an identity (ID) of an SNS friend of the member to the PoX blockchain platform server, a registering step in which the PoX blockchain platform server newly registers the ID of the SNS friend as a blockchain membership node, and a reward rate determining step in which the PoX blockchain platform server determines a reward rate for each blockchain member in association with the number of SNS friend IDs that the blockchain member recommends.

Abstract: A semiconductor package and a method of manufacturing a semiconductor package are provided. The semiconductor package includes a first substrate having electrodes are disposed on both surfaces thereof, one or more first elements mounted on a first surface of the first substrate, a first insulating member comprising an insulating material disposed on a first surface of the first substrate and affixing one or more first elements to the first surface of the first substrate, and one or more second elements mounted on a second surface of the first substrate. At least a portion of the first elements is externally exposed from the first insulating member.

Abstract: Disclosed is an antihypertensive composition containing as an active ingredient a gelatin extract made from the skins of a skate ray and a peptide isolated from the extract. The present invention is directed to a pharmaceutical composition for a hypertension prevention and therapy containing as an active ingredient a hydrolysate of a gelatin extract isolated from the skins of a skate ray, a method for preparing a hydrolysate of a gelatin extract made from the skins of a skate ray, and the use of a new peptide having an antihypertensive activity isolated and purified from the hydrolysate.

Abstract: Disclosed are a pharmaceutical composition for a sexual function improvement, an erection dysfunction therapy agent containing the urechis unicinctus as an effective component, a health function food for a sexual function improvement and a method for preparing an urechis unicinctus extract with a sexual function improvement activation each of which contains an urechis unicinctus extract which is added as an effective component and yielded by way of a process at a temperature 100˜130° C. at a pressure of 1 Kgf/cm2 for 20˜40 minutes and then with an ultrasonic wave at a frequency 35˜45 KHz for 50˜70 minutes.