Patents by Inventor Miseon BAE

Miseon BAE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538498
    Abstract: The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: January 21, 2020
    Assignee: Chong Kun Dang Pharmaceutical Corp.
    Inventors: Jaekwang Lee, Younghue Han, Yuntae Kim, Daekyu Choi, Jaeki Min, Miseon Bae, Hyunmo Yang, Dohoon Kim
  • Patent number: 10464911
    Abstract: The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: November 5, 2019
    Assignee: Chong Kun Dang Pharmaceutical Corp.
    Inventors: Jaekwang Lee, Younghue Han, Yuntae Kim, Jaeki Min, Miseon Bae, Dohoon Kim, Seokmin Jin, Jangbeen Kyung
  • Patent number: 10287255
    Abstract: A compound of formula (I), having histone deacetylase 6 (HDAC6) inhibitory activity, wherein X, Q, N, R1, R2, L, and n are as described, isomers thereof, or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions comprising the same, a method of treating disease using the composition, and methods for preparing the novel compounds. The novel compounds according to the present invention have histone deacetylase 6 (HDAC6) inhibitory activity, and are effective for the prevention or treatment of HDAC6-associated diseases, including cancer, inflammatory diseases, autoimmune diseases, neurological diseases and neurodegenerative disorders.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: May 14, 2019
    Assignee: CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Hyeseung Song, Changgon Lee, Dalyong Kwak, Jaeyoung Lee, Suyeal Bae, Yuntae Kim, Daekwon Bae, Nina Ha, Miseon Bae, Jihyun Kim
  • Publication number: 20180251437
    Abstract: The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. (I) The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases.
    Type: Application
    Filed: July 27, 2016
    Publication date: September 6, 2018
    Inventors: Jaekwang Lee, Younghue Han, Yuntae Kim, Daekyu Choi, Jaeki Min, Miseon Bae, Hyunmo Yang, Dohoon Kim
  • Publication number: 20180230113
    Abstract: The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 16, 2018
    Inventors: Jaekwang Lee, Younghue Han, Yuntae Kim, Jaeki Min, Miseon Bae, Dohoon Kim, Seokmin Jin, Jangbeen Kyung
  • Patent number: 9650379
    Abstract: The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: May 16, 2017
    Assignee: CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Changsik Lee, Hyun-Mo Yang, Changkon Lee, Miseon Bae, Soyoung Kim, Youngil Choi, Nina Ha, Jaekwang Lee, Jungtaek Oh, Hyeseung Song, Ilhyang Kim, Daekyu Choi, Jaeki Min, Hyojin Lim, Daekwon Bae
  • Publication number: 20170096405
    Abstract: The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, isomers thereof, or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions comprising the same, a method of treating disease using the composition, and methods for preparing the novel compounds. The novel compounds according to the present invention have histone deacetylase 6 (HDAC6) inhibitory activity, and are effective for the prevention or treatment of HDAC6-associated diseases, including cancer, inflammatory diseases, autoimmune diseases, neurological diseases and neurodegenerative disorders.
    Type: Application
    Filed: March 12, 2015
    Publication date: April 6, 2017
    Applicant: CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Hyeseung SONG, Changgon LEE, Dalyong KWAK, Jaeyoung LEE, Suyeal BAE, Yuntae KIM, Daekwon BAE, Nina HA, Miseon BAE, Jihyun KIM
  • Publication number: 20160355475
    Abstract: The present invention provides a novel indole derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof. The compound according to the present invention can selectively inhibit histone deacetylase (HDAC), and thus can be used to effectively treat a disease associated with histone deacetylase (HDAC) activity.
    Type: Application
    Filed: January 2, 2015
    Publication date: December 8, 2016
    Applicant: CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Changsik LEE, Hyun-Mo YANG, Dohoon KIM, Miseon BAE, Youngil CHOI, Nina HA
  • Publication number: 20160289230
    Abstract: The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.
    Type: Application
    Filed: December 12, 2014
    Publication date: October 6, 2016
    Applicant: CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Changsik LEE, Hyun-Mo YANG, Changkon LEE, Miseon BAE, Soyoung KIM, Youngil CHOI, Nina HA, Jaekwang LEE, Jungtaek OH, Hyeseung SONG, Ilhyang KIM, Daekyu CHOI, Jaeki MIN, Hyojin LIM, Daekwon BAE