Patents by Inventor Mian Chen
Mian Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12241823Abstract: The present disclosure provides a technology field of caking of crystal particles, and in particular relates to a method for predicting a critical caking cycle of crystal particle. The method includes: establishing a CHS crystal bridge growth model database of a crystal particle with a same type of crystal particle to be predicted firstly, selecting existed data in the corresponding CHS crystal bridge growth model database based on an equivalent particle radius, a stored ambient temperature, and an environmental high and low humidity cycle condition of the crystal particle to be predicted, respectively, and calculating the critical caking cycle according to experience calculation equations, wherein a result obtained by calculation is a predicted critical caking cycle of the crystal particle to be predicted.Type: GrantFiled: May 7, 2024Date of Patent: March 4, 2025Assignees: TIANJIN UNIVERSITY, ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., ZHEJIANG INSTITUTE OF TIANJIN UNIVERSITY (SHAOXING)Inventors: Junbo Gong, Mian Li, Mingyang Chen, Wulong Yang, Jiahui Li, Mingxuan Li, Qiang Wu, Baohong Hou, Qiuxiang Yin
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Publication number: 20250067179Abstract: The present disclosure provides a monitoring and warning device for rock burst in coal mine, which is configured for monitoring a rock mass in a drill hole, the monitoring and warning device for rock burst in coal mine includes: an integration rod, radial adjustment components, a plurality of bases, and a measuring instrument, the integration rod is extended into the drill hole; the radial adjustment components are provided on the integration rod, and have a plurality of radial adjustment ends; a plurality of bases are correspondingly provided in the radial adjustment ends, and the bases are further connected with attachment components through elastic components, and the attachment components are embedded with first strain gauges; the measuring instrument is rotatably provided in the integration rod, and is used to measure the distance between the measuring instrument and the attachment components.Type: ApplicationFiled: August 6, 2024Publication date: February 27, 2025Inventors: Hongtu ZHANG, Mian WANG, Zhibo ZHANG, Chao GUO, Xiangyang WANG, Fenggang ZHANG, Dong CHEN, Pan CHEN, Duzhou LI, Liuqun DU, Lianbo HUANG, Jinhua LI, Junfang LI, He SUN, Zhen LI, Gongda WANG, Xu CHEN, Weiyong LU
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Patent number: 12234732Abstract: The present disclosure provides a monitoring and warning device for rock burst in coal mine, which is configured for monitoring a rock mass in a drill hole, the monitoring and warning device for rock burst in coal mine includes: an integration rod, radial adjustment components, a plurality of bases, and a measuring instrument, the integration rod is extended into the drill hole; the radial adjustment components are provided on the integration rod, and have a plurality of radial adjustment ends; a plurality of bases are correspondingly provided in the radial adjustment ends, and the bases are further connected with attachment components through elastic components, and the attachment components are embedded with first strain gauges; the measuring instrument is rotatably provided in the integration rod, and is used to measure the distance between the measuring instrument and the attachment components.Type: GrantFiled: August 6, 2024Date of Patent: February 25, 2025Assignee: Henan Polytechnic UniversityInventors: Hongtu Zhang, Mian Wang, Zhibo Zhang, Chao Guo, Xiangyang Wang, Fenggang Zhang, Dong Chen, Pan Chen, Duzhou Li, Liuqun Du, Lianbo Huang, Jinhua Li, Junfang Li, He Sun, Zhen Li, Gongda Wang, Xu Chen, Weiyong Lu
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Patent number: 12140719Abstract: A correction method for a microseism interpretation fracturing fracture parameter result. The method includes classifying the communication modes of a block sampling fractured wells to be corrected according to the matching degree of micro seismic monitoring result and sand adding amount; correcting the volume coefficient of each said classified fractured well single well, and the volume correction coefficient Bv of each said fractured well is: B v = [ L 5 / 4 ? H ] T [ L 5 / 4 ? H ] W , wherein, [L5/4H]W is a calculation value of a micro seismic monitoring interpretation result; [L5/4H]T is a theoretical calculation value obtained by using field construction parameters; C, calculating the classification volume correction coefficient of each class of fractured wells according to the calculated single well volume correction coefficient of each said fractured well.Type: GrantFiled: July 7, 2020Date of Patent: November 12, 2024Assignee: CHINA UNIVERSITY OF PETROLEUM (BEIJING)Inventors: Bing Hou, Yue Xiao, Yan Jin, Bowen Cao, Mian Chen
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Publication number: 20240207396Abstract: An oligosaccharide vaccine for specific prevention of fungal infections and a method for preparing the same are provided. The vaccine is formed by conjugating a sulfhydrylated protein with oligosaccharide. The sulfhydrylated protein is formed by introducing a sulfhydryl group (—SH) to a carrier protein containing a primary amino group (—NH2), and then is conjugated with the oligosaccharide to form the oligosaccharide vaccine under the binding action of a bridging agent. The carrier protein is a non-humanized protein, and the oligosaccharide is a chitosan oligosaccharide mixture and/or chitin oligosaccharide mixture. The vaccine has strong immunogenicity, can activate Th17 cell immunity, and can recognize and protect infections caused by fungi.Type: ApplicationFiled: July 13, 2021Publication date: June 27, 2024Applicant: SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCESInventors: Fei LIU, Dandan YUAN, lei CHEN, Linlin NIU, Mian CHEN, Huarong SHAO, Xiaogang ZHANG, Yingmei LIU, Jinhua ZHANG, Mengqi DIAO, Xinyan GUO
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Publication number: 20220206174Abstract: A correction method for a microseism interpretation fracturing fracture parameter result. The method includes classifying the communication modes of a block sampling fractured wells to be corrected according to the matching degree of micro seismic monitoring result and sand adding amount; correcting the volume coefficient of each said classified fractured well single well, and the volume correction coefficient By of each said fractured well is: B v = [ L 5 / 4 ? H ] T [ L 5 / 4 ? H ] W , wherein, [L5/4H]W is a calculation value of a micro seismic monitoring interpretation result; [L5/4H]T is a theoretical calculation value obtained by using field construction parameters; C, calculating the classification volume correction coefficient of each class of fractured wells according to the calculated single well volume correction coefficient of each said fractured well.Type: ApplicationFiled: July 7, 2020Publication date: June 30, 2022Inventors: Bing HOU, Yue XIAO, Yan JIN, Bowen CAO, Mian CHEN
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Patent number: 11360235Abstract: A modeling method is provided. The modeling method includes: extracting multiple pieces of logging data corresponding to a plurality of logging characteristic parameters at different drilling depths of a sample well, based on a logging information of the sample well; marking the different drilling depths based on a lost circulation information of the sample well to distinguish lost circulation points and non-lost circulation points; and classifying the lost circulation points and the non-lost circulation points by adopting a random forest algorithm, based on the plurality of logging characteristic parameters and the multiple pieces of marked logging data at the different drilling depths, to establish a plurality of corresponding relations between the logging characteristic parameters and a lost circulation or non-lost circulation result, so as to obtain a diagnosis model.Type: GrantFiled: August 2, 2019Date of Patent: June 14, 2022Assignee: China University of Petroleum (Beijing)Inventors: Yunhu Lu, Yan Jin, Mian Chen, Zejun Li, Hanqing Wang, Yang Xia, Zhou Zhou, Bing Hou, Botao Lin, Xuyang Guo
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Publication number: 20200191994Abstract: A modeling method is provided. The modeling method includes: extracting multiple pieces of logging data corresponding to a plurality of logging characteristic parameters at different drilling depths of a sample well, based on a logging information of the sample well; marking the different drilling depths based on a lost circulation information of the sample well to distinguish lost circulation points and non-lost circulation points; and classifying the lost circulation points and the non-lost circulation points by adopting a random forest algorithm, based on the plurality of logging characteristic parameters and the multiple pieces of marked logging data at the different drilling depths, to establish a plurality of corresponding relations between the logging characteristic parameters and a lost circulation or non-lost circulation result, so as to obtain a diagnosis model.Type: ApplicationFiled: August 2, 2019Publication date: June 18, 2020Applicant: China University of Petroleum (Beijing)Inventors: Yunhu LU, Yan JIN, Mian CHEN, Zejun LI, Hanqing WANG, Yang XIA, Zhou ZHOU, Bing HOU, Botao LIN, Xuyang GUO
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Patent number: 10550688Abstract: Apparatus and method for a physical simulation experiment of fracturing an unconventional oil and gas reservoir layer by layer by spiral perforation via a horizontal well bore. The apparatus includes an outer wellbore provided with at least three layers of spiral perforations, and an inner wellbore provided with at least three layers of through-holes. The method includes injecting fracturing fluid into the inner wellbore, and opening a first layer cracks of a stratum by the fracturing fluid passing the first through-hole layer and the first spiral perforation layer, opening a second layer cracks of the stratum by the fracturing fluid passing second through-hole layer and second spiral perforation layer and opening a third layer cracks of the stratum by the fracturing fluid passing third through-hole layer and third spiral perforation layer.Type: GrantFiled: December 29, 2017Date of Patent: February 4, 2020Assignee: China University of Petroleum—BeijingInventors: Bing Hou, Zhi Chang, Yan Jin, Mian Chen, Yunhu Lu, Botao Lin, Zhou Zhou, Peng Tan
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Publication number: 20190055838Abstract: Apparatus and method for a physical simulation experiment of fracturing an unconventional oil and gas reservoir layer by layer by spiral perforation via a horizontal well bore. The apparatus includes an outer wellbore provided with at least three layers of spiral perforations, and an inner wellbore provided with at least three layers of through-holes. The method includes injecting fracturing fluid into the inner wellbore, and opening a first layer cracks of a stratum by the fracturing fluid passing the first through-hole layer and the first spiral perforation layer, opening a second layer cracks of the stratum by the fracturing fluid passing second through-hole layer and second spiral perforation layer and opening a third layer cracks of the stratum by the fracturing fluid passing third through-hole layer and third spiral perforation layer.Type: ApplicationFiled: December 29, 2017Publication date: February 21, 2019Inventors: Bing HOU, Zhi CHANG, Yan JIN, Mian CHEN, Yunhu LU, Botao LIN, Zhou ZHOU, Peng TAN
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Publication number: 20030232099Abstract: A multifunction health-care product and methods for preparing and using the same are provided. The health-care product contains a powder of lotus root joints and/or an extract of the joints as the main active ingredient. A preferred composition of the product contains 4-7.5 parts by weight extract of the joints, 2-15 parts by weight powder of lotus root joints, 0.08 to 2 parts by weight green tea and/or an extract thereof, and 0.08 to 0.5 parts by weight notoginseng and/or an extract thereof. The method for the preparation of the composition involves directly pulverizing the lotus root joints, putting the pulverized lotus root joints in product-grade solvent for extraction, and then filtering it to obtain a filtrate solution which is the extract of the joints. The health-care product can effectively improve IR, thus improving and preventing type-II diabetes mellitus, hypertension, hyperlipoidemia, and cardio-cerebral vascular diseases caused by being obese, and also has the effect of effecting weight loss.Type: ApplicationFiled: June 4, 2003Publication date: December 18, 2003Applicant: Yunnan Baiyao Group Co., Ltd.Inventors: Ling Pan, Deliang Li, Liqun Zhang, Wenxu Tang, Chengjin Yang, Chongkun Gao, You Feng, Mian Chen
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Patent number: 5925529Abstract: This invention relates to peptide ligand discovery and is particularly directed to a method for the discovery of agonists for membrane bound receptors. The inventive detection system involves the use of a "tethered" ligand for probing receptor binding. The general detection system includes a membrane, a membrane bound receptor, and a chimeric ligand presenting molecule. This chimeric protein forms the tethered ligand and in turn includes a membrane domain, a linker domain, a ligand domain, and a cleavable terminal domain. The "ligands" of the system are exposed by the addition of a specific peptidase that cleaves at the designated sequence. The sequence of the ligand that produces signal as a result of the interaction between the agonist and receptor can be then be isolated using sib selection.Type: GrantFiled: June 7, 1995Date of Patent: July 20, 1999Assignee: The Regents of the University of CaliforniaInventors: Shaun R. Coughlin, Ji Chen, Harold Bernstein, Maki Ishii, Ling Wang, Mian Chen