Patents by Inventor Mian Li

Mian Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12281183
    Abstract: The embodiments of the present disclosure provide a method for extracting xylose liquid and cellulose with high purity from corn straw. The method includes raw material screening, raw material preprocessing, alkali processing, acid hydrolysis, and gradient alkali processing. The embodiments of the present disclosure adopt a gradient selective refining method for extracting a high-purity xylose liquid and cellulose from the corn straw, so as to maximize the extraction of the xylose from the corn straw, and at the same time, to separate and extract a high-purity cellulose product from straw residue under a low-cost process processing.
    Type: Grant
    Filed: April 30, 2024
    Date of Patent: April 22, 2025
    Assignee: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Mian Li, Changhui Hu, Liangcong Yan, Jiaxing Luo, Wulong Yang, Weidong Xu, Qiang Wu
  • Publication number: 20250097575
    Abstract: Imaging systems and techniques are described. An imaging system receives image data captured by an image sensor according to one or more image capture settings, for instance according to an aperture size, temperature, lux, lens position, and/or region of interest. The image data includes image pixel data and focus pixel data. The imaging system determines a first focus setting based on phase detection using the focus pixel data. The imaging system determines a focus offset based on use of the one or more image capture settings as inputs to a trained model (e.g., decision tree, random forest, neural network). The imaging system determines a second focus setting at least in part by adjusting the first focus setting according to the focus offset, and causes a focus control mechanism to set a focus parameter to the second focus setting.
    Type: Application
    Filed: March 24, 2022
    Publication date: March 20, 2025
    Inventors: Wen-Chun FENG, Hsuan-Ming LIU, Mian LI
  • Patent number: 12241823
    Abstract: The present disclosure provides a technology field of caking of crystal particles, and in particular relates to a method for predicting a critical caking cycle of crystal particle. The method includes: establishing a CHS crystal bridge growth model database of a crystal particle with a same type of crystal particle to be predicted firstly, selecting existed data in the corresponding CHS crystal bridge growth model database based on an equivalent particle radius, a stored ambient temperature, and an environmental high and low humidity cycle condition of the crystal particle to be predicted, respectively, and calculating the critical caking cycle according to experience calculation equations, wherein a result obtained by calculation is a predicted critical caking cycle of the crystal particle to be predicted.
    Type: Grant
    Filed: May 7, 2024
    Date of Patent: March 4, 2025
    Assignees: TIANJIN UNIVERSITY, ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., ZHEJIANG INSTITUTE OF TIANJIN UNIVERSITY (SHAOXING)
    Inventors: Junbo Gong, Mian Li, Mingyang Chen, Wulong Yang, Jiahui Li, Mingxuan Li, Qiang Wu, Baohong Hou, Qiuxiang Yin
  • Patent number: 12187667
    Abstract: Disclosed is a preparation system and a preparation method for high-quality xylitol crystals. The preparation system comprises a blending tank, a heat exchanger, a decolorization tank, an ion exchange system, a microporous filter, a first evaporator, a first crystallization kettle, a first centrifuge, a fluidization drying bed, a xylitol dissolution tank, a second evaporator, a second crystallization kettle, a second centrifuge, a hot air drying tank, and a cold air fluidization bed sequentially connected through pipelines. Liquid outlet of the first centrifuge is connected with first inlet of the blending tank. Liquid outlet of the second centrifuge is connected with first inlet of the xylitol dissolution tank. The blending tank is provided with second inlet for receiving xylitol hydrogenation solution. The xylitol dissolution tank is provided with water inlet for pure water. The material output from a product outlet of the cold air fluidization bed is xylitol crystal product.
    Type: Grant
    Filed: May 7, 2024
    Date of Patent: January 7, 2025
    Assignee: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Qiang Wu, Mian Li, Wenyao Zhang, Wulong Yang, Weidong Xu, Shufang Qin, Ni Zhen
  • Publication number: 20240344954
    Abstract: The present disclosure provides a technology field of caking of crystal particles, and in particular relates to a method for predicting a critical caking cycle of crystal particle. The method includes: establishing a CHS crystal bridge growth model database of a crystal particle with a same type of crystal particle to be predicted firstly, selecting existed data in the corresponding CHS crystal bridge growth model database based on an equivalent particle radius, a stored ambient temperature, and an environmental high and low humidity cycle condition of the crystal particle to be predicted, respectively, and calculating the critical caking cycle according to experience calculation equations, wherein a result obtained by calculation is a predicted critical caking cycle of the crystal particle to be predicted.
    Type: Application
    Filed: May 7, 2024
    Publication date: October 17, 2024
    Applicants: TIANJIN UNIVERSITY, ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., ZHEJIANG INSTITUTE OF TIANJIN UNIVERSITY (SHAOXING)
    Inventors: Junbo GONG, Mian LI, Mingyang CHEN, Wulong YANG, Jiahui LI, Mingxuan LI, Qiang WU, Baohong HOU, Qiuxiang YIN
  • Patent number: 12098410
    Abstract: Recombinant Zymomonas mobilis for producing ethylene glycol, method and uses thereof are provided. The recombinant Zymomonas mobilis carries and expresses genes related to a synthesis pathway of xylonic acid and genes related to a synthesis pathway of ethylene glycol.
    Type: Grant
    Filed: December 31, 2023
    Date of Patent: September 24, 2024
    Assignee: Hubei University
    Inventors: Shihui Yang, Xiongying Yan, Mian Li, Xia Wang, Qiaoning He
  • Patent number: 12091364
    Abstract: The disclosure provides an MAX phase material, a preparation method therefor, and application thereof. The molecular formula of the MAX phase material is represented as Mn+1(AzA?1?z)hXn, wherein M is selected from group IIIB, IVB, VB or VIB elements, A is selected from element Zn, Cu, Ni, Co, Fe or Mn, A? is selected from group IB, IIB, VIII, IVA, VA or VIA elements, X is selected from elements C and/or N, n is 1, 2, 3 or 4, 0<z?1, a unit cell of the MAX phase material is formed by alternately stacking Mn+1Xn units and (AzAzA?1?z)h layers of atoms, and h is the number of layers of the (AzAzA?1?z) layers of atoms located between the Mn+1Xn unit layers, and h is 1, 2 or 3.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: September 17, 2024
    Assignee: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCE
    Inventors: Qing Huang, Mian Li, Youbing Li, Xiaobing Zhou, Kan Luo, Shiyu Du, Zhengren Huang
  • Publication number: 20240301094
    Abstract: The embodiments of the present disclosure provide a method for extracting xylose liquid and cellulose with high purity from corn straw. The method includes raw material screening, raw material preprocessing, alkali processing, acid hydrolysis, and gradient alkali processing. The embodiments of the present disclosure adopt a gradient selective refining method for extracting a high-purity xylose liquid and cellulose from the corn straw, so as to maximize the extraction of the xylose from the corn straw, and at the same time, to separate and extract a high-purity cellulose product from straw residue under a low-cost process processing.
    Type: Application
    Filed: April 30, 2024
    Publication date: September 12, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Mian LI, Changhui HU, Liangcong YAN, Jiaxing LUO, Wulong YANG, Weidong XU, Qiang WU
  • Publication number: 20240301448
    Abstract: Recombinant Zymomonas mobilis for producing ethylene glycol, method and uses thereof are provided. The recombinant Zymomonas mobilis carries and expresses genes related to a synthesis pathway of xylonic acid and genes related to a synthesis pathway of ethylene glycol.
    Type: Application
    Filed: December 31, 2023
    Publication date: September 12, 2024
    Applicant: Hubei University
    Inventors: Shihui YANG, Xiongying YAN, Mian LI, Xia WANG, Qiaoning HE
  • Publication number: 20240300877
    Abstract: The present disclosure provides a method for co-producing a xylitol and a caramel pigment. The method includes: transporting a raw material of a xylose mother liquid in a raw material tank to a filter for filtering impurities to obtain a filtered raw material of the xylose mother liquid, and transporting the filtered raw material of the xylose mother liquid to a nanofiltration membrane device to obtain a decolorized xylose mother liquid; transporting the decolorized xylose mother liquid to a first ion exchange device to obtain an ion exchange liquid; and transporting the ion exchange liquid to a chromatographic separation device and obtaining an extracted liquid and a raffinate liquid; performing a refined hydrogenation process on the extracted liquid through a refined hydrogenation assembly to obtain a crystal xylitol, and performing a browning reaction process on the raffinate liquid through a browning reaction assembly to obtain the caramel pigment.
    Type: Application
    Filed: May 10, 2024
    Publication date: September 12, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Mian LI, Weidong XU, Deshui CHEN, Xinping CHENG, Chengjun LIAO, Qiang WU, Wulong YANG, Shufang QIN
  • Publication number: 20240286983
    Abstract: The present disclosure provides a preparation system and a preparation method for xylitol crystals. In the preparation system, outlets of a first centrifuge are connected with an inlet of a hot air drying tank and an inlet of a primary mother liquor storage tank through pipelines, respectively. Outlets of a second centrifuge are connected with an inlet of a second fluidized bed dryer and an inlet of a secondary mother liquor storage tank through pipelines, respectively. An outlet of a dicrystalline sugar dissolution tank is connected with an inlet of a blending tank through pipeline. An outlet of a tricrystalline sugar dissolution tank is connected with the inlet of the primary mother liquor storage tank. The blending tank is provided with an inlet for a raw material of xylitol hydrogenation solution. An output of an outlet of a first fluidized bed dryer is prepared xylitol crystals.
    Type: Application
    Filed: May 6, 2024
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Qiang WU, Mian LI, Wulong YANG, Fuan WAN, Weidong XU, Shufang QIN, Hang YUE, Weijia WANG
  • Publication number: 20240286984
    Abstract: Disclosed is a preparation system and a preparation method for high-quality xylitol crystals. The preparation system comprises a blending tank, a heat exchanger, a decolorization tank, an ion exchange system, a microporous filter, a first evaporator, a first crystallization kettle, a first centrifuge, a fluidization drying bed, a xylitol dissolution tank, a second evaporator, a second crystallization kettle, a second centrifuge, a hot air drying tank, and a cold air fluidization bed sequentially connected through pipelines. Liquid outlet of the first centrifuge is connected with first inlet of the blending tank. Liquid outlet of the second centrifuge is connected with first inlet of the xylitol dissolution tank. The blending tank is provided with second inlet for receiving xylitol hydrogenation solution. The xylitol dissolution tank is provided with water inlet for pure water. The material output from a product outlet of the cold air fluidization bed is xylitol crystal product.
    Type: Application
    Filed: May 7, 2024
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Qiang WU, Mian LI, Wenyao ZHANG, Wulong YANG, Weidong XU, Shufang QIN, Ni ZHEN
  • Publication number: 20240287550
    Abstract: The present disclosure provides a system and a method for utilizing corn cobs to jointly produce a premium xylose and a high-end caramel pigment. The system includes a xylose preparation subsystem, an enzymatic hydrolysis subsystem, and a caramel pigment preparation subsystem that are connected to each other through pipelines. The xylose preparation subsystem includes a raw material tank, a pretreatment tank, an acid hydrolysis kettle, a plate and frame filter press device, a filtrate neutralization tank, a nanofiltration membrane separator, an electrodialysis separator, an evaporation concentration tank, a crystallization tank, a centrifugal separator, and a dryer that are connected in sequence through pipelines. The enzymatic hydrolysis subsystem includes a filter residue neutralization tank and an enzymatic hydrolysis reaction kettle connected through pipelines.
    Type: Application
    Filed: May 6, 2024
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Weidong XU, Mian LI, Wulong YANG, Qiang WU, Shufang QIN, Jingjing XU, Zhihui YAO
  • Publication number: 20240287630
    Abstract: The embodiment of the present disclosure provides a method for crystallizing compound sugar solution of xylose and sucrose, including: evaporating a mixed solution containing sucrose and xylose to obtain an evaporated mixed solution, adjusting a temperature to a range of 70° C.-75° C., dropwise adding an organic solvent to the evaporated mixed solution, adding sucrose seed crystals, and continuing stirring to obtain a solution, when seed crystals grow in the solution, dropping the temperature to a range of 40° C.-60° C. at a rate of 10° C./h to obtain the mixed sugar solution; centrifuging and drying to obtain a finished product of the compound sugar crystals of the xylose and the sucrose. The obtained finished product has a complete crystal form similar to the sucrose and a sweetness similar to the sucrose and a uniform taste, which meets preferences of the consumers.
    Type: Application
    Filed: May 5, 2024
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Shufang QIN, Mian LI, Qiang WU, Wulong YANG, Huan ZHOU, Yinyin LIU, Jiangen YAN
  • Publication number: 20240284950
    Abstract: The present disclosure discloses systems and methods for preparing compound crystals of erythritol and high-intensity sweeteners. The systems may comprise a fermentation liquid storage tank, a ceramic membrane filtration system, a nanofiltration system, a first evaporator, a first crystallization kettle, a first centrifuge, a sugar dissolution tank, a decolorization tank, an ion exchange column, a blending tank, a second evaporator, a second crystallization kettle, a second centrifuge, a hot-air drying tank, a fluidized drying bed, and a finished product tank sequentially connected through pipelines. The systems may further comprise a high-intensity sweetener storage tank, a primary mother liquor tank, and a secondary mother liquor tank. The finished product tank may store a prepared compound crystallization product of the erythritol and the high-intensity sweetener.
    Type: Application
    Filed: April 30, 2024
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Shufang QIN, Mian LI, Wenyao ZHANG, Wulong YANG, Qiang WU, Ni ZHEN, Weidong XU
  • Publication number: 20240249423
    Abstract: Systems and techniques are provided for processing one or more images. For instance, aspects include a process that can include determining a first region of interest corresponding to a first object depicted in an image obtained using at least one camera. The first region of interest is associated with at least one element of a multi-point grid associated with a multi-point depth sensing system. The process can include determining a first extended region of interest for the first object. The first extended region of interest is associated with a plurality of elements including the at least one element and one or more additional elements of the multi-point grid. The process can further include, based on the plurality of elements associated with the first extended region of interest, determining representative depth information representing a first distance between the at least one camera and the first object depicted in the image.
    Type: Application
    Filed: July 7, 2021
    Publication date: July 25, 2024
    Inventors: Wen-Chun FENG, Mian LI, Hui Shan KAO
  • Publication number: 20240242358
    Abstract: Techniques and systems are provided for improving one or more image capture operations. In some examples, a system determines, based on data from one or more sensors, a movement of an image capture device associated with a capture of a plurality of image frames. The systems adjust a position of at least one object in each of the plurality of image frames based on the movement of the image capture device. The system determines a motion of the at least one object based on a difference in the adjusted position among the plurality of image frames. The system selects a value for at least one image capture parameter associated with the plurality of image frames based on the motion of the at least one object.
    Type: Application
    Filed: July 7, 2021
    Publication date: July 18, 2024
    Inventors: Wen-Chun FENG, Wei-Chih LIU, Mian LI, Ruocheng JIANG
  • Patent number: 12012430
    Abstract: The present disclosure relates to a method for preparing liquid maltitol and liquid polyols from a raffinate including maltitol. The method comprises the following steps: obtaining a hydrogenated liquid by hydrogenating a pre-treated raffinate including maltitol, obtaining a post-treated liquid by post-treatment of the hydrogenated liquid to remove impurities, obtaining a dilute liquid and a concentrated maltitol solution by membrane-separation of the post-treated liquid, and using the dilute liquid as the liquid polyols, and obtaining the liquid maltitol by mixing the concentrated maltitol solution with a prepared maltitol solution with a maltitol content of over 50%, wherein the liquid maltitol has a maltitol content greater than or equal to 50% and meets a standard. Before the membrane separation process, the present disclosure reduces the reducing sugar content in the liquid by hydrogenation to lower the risk of yellowing during the process and to improve the quality of the final product.
    Type: Grant
    Filed: September 18, 2023
    Date of Patent: June 18, 2024
    Assignee: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Yanhui Yao, Xinfeng Han, Fuan Wan, Hang Yue, Weixing Shen, Haojun Dai, Mingqian Yang, Mian Li
  • Publication number: 20240189553
    Abstract: Balloon catheter (22) having a coating comprises a primer layer (24) comprising at least one or more substantially hydrophilic compounds, a first layer (26) comprising an inclusion compound; and a second layer (28) comprising a mixture of a hydrophobic polymer, an active therapeutic agent and the inclusion compound.
    Type: Application
    Filed: April 12, 2021
    Publication date: June 13, 2024
    Applicant: OrbusNeich Medical (Shenzhen) Co., Ltd.
    Inventors: Songyun XU, Lin WAN, Jingjing ZHU, Yirong GONG, Chang PENG, Mian LI, Xueying WEI
  • Patent number: 12006281
    Abstract: The embodiment of the present disclosure provides a system for co-producing a xylitol and a caramel pigment by utilizing a xylose mother liquid, including an extraction assembly, a refined hydrogenation assembly and a browning reaction assembly. The extraction assembly is configured to obtain an extracted liquid and a raffinate liquid respectively by performing an initial extraction on the xylose mother liquid; the refined hydrogenation assembly is configured to prepare a crystal xylitol by performing a refined hydrogenation process on the extracted liquid; the browning reaction assembly is configured to prepare the caramel pigment by performing a browning reaction process on the raffinate liquid.
    Type: Grant
    Filed: July 7, 2023
    Date of Patent: June 11, 2024
    Assignee: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
    Inventors: Mian Li, Weidong Xu, Deshui Chen, Xinping Cheng, Chengjun Liao, Qiang Wu, Wulong Yang, Shufang Qin