Patents by Inventor Miao Ping
Miao Ping has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220090007Abstract: According to one method, a sample with cells contains a phototagging agent. The sample is imaged to identify at least one target cell to be isolated. The identified target cell in the sample is selectively irradiated with photo-activating light for selectively activating the phototagging agent in the target cell to change its fluorescence response. The irradiated target cell is isolated from other cells in the sample based on a difference in its fluorescence response compared to non-activated phototagging agent in the other cells. Further aspects are directed to a corresponding microscope system and chemical compound for use as the phototagging agent.Type: ApplicationFiled: January 21, 2020Publication date: March 24, 2022Applicant: ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAMInventor: Miao-Ping CHIEN
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Patent number: 10077463Abstract: Provided herein are photochemical crosslinkers and photocleavable crosslinkers and their uses in methods for cell selection from cell cultures. The photochemical crosslinkers comprise a fluorescent dye and a radical generator. The photocleavable crosslinkers comprise a photocleavable linker linking two electrophilic groups to each other. Also provided are systems for imaging cells comprising a plurality of cells crosslinked to extracellular matrix proteins using a crosslinker as described, an imaging apparatus, an illuminating apparatus, and software for image processing.Type: GrantFiled: January 14, 2016Date of Patent: September 18, 2018Assignee: President and Fellows of Harvard CollegeInventors: Adam E. Cohen, Miao-Ping Chien
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Publication number: 20160208308Abstract: Provided herein are photochemical crosslinkers and photocleavable crosslinkers and their uses in methods for cell selection from cell cultures. The photochemical crosslinkers comprise a fluorescent dye and a radical generator. The photocleavable crosslinkers comprise a photocleavable linker linking two electrophilic groups to each other. Also provided are systems for imaging cells comprising a plurality of cells crosslinked to extracellular matrix proteins using a crosslinker as described, an imaging apparatus, an illuminating apparatus, and software for image processing.Type: ApplicationFiled: January 14, 2016Publication date: July 21, 2016Applicant: President and Fellows of Harvard CollegeInventors: Adam E. Cohen, Miao-Ping Chien
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Patent number: 9040626Abstract: The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.Type: GrantFiled: February 1, 2012Date of Patent: May 26, 2015Assignee: The Regents of the University of CaliforniaInventors: Miao-Ping Chien, Nathan C. Gianneschi
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Patent number: 8604721Abstract: A lamp tube switching circuit includes a first connector and a second connector for connecting either an LED lamp tube or a fluorescent type lamp tube, a switch module being a mechanical switch including first, second and third switches, a starter and ballast. Each of the first and second switches has a static terminal for connecting with a power supply, and four dynamic terminals for selectively connecting with the static terminal thereof. Different circuits can be configured by adjusting the connection between the static and dynamic terminals, wherein each circuit can drive a selected type of lamp tube to generate light.Type: GrantFiled: August 22, 2011Date of Patent: December 10, 2013Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.Inventors: Qing-Shan Cao, Zheng-Nian Liu, Nan Zeng, Miao-Ping Guo
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Patent number: 8403692Abstract: An illumination device includes a light tube holder including two connectors for receiving either a light-emitting diode (LED) tube or a fluorescent tube. One of the connectors includes a rotary member rotatably received in a through hole defined in a retainer, and four conductive elastic pieces positioned in the retainer around the through hole. Two of the conductive pieces are electrically connected to an LED tube drive circuit board and the other two are connected to a fluorescent tube drive circuit board. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.Type: GrantFiled: November 22, 2011Date of Patent: March 26, 2013Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.Inventors: Qing-Shan Cao, Yu Hu, Zheng-Nian Liu, Miao-Ping Guo
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Publication number: 20130002170Abstract: An illumination device includes a light tube holder including two connectors for receiving either a light-emitting diode (LED) tube or a fluorescent tube. One of the connectors includes a rotary member rotatably received in a through hole defined in a retainer, and four conductive elastic pieces positioned in the retainer around the through hole. Two of the conductive pieces are electrically connected to an LED tube drive circuit board and the other two are connected to a fluorescent tube drive circuit board. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.Type: ApplicationFiled: November 22, 2011Publication date: January 3, 2013Applicants: HON HAI PRECISION INDUSTRY CO., LTD., HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD.Inventors: QING-SHAN CAO, YU HU, ZHENG-NIAN LIU, MIAO-PING GUO
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Publication number: 20130002152Abstract: A lamp tube switching circuit includes a first connector and a second connector for connecting either an LED lamp tube or a fluorescent type lamp tube, a switch module being a mechanical switch including first, second and third switches, a starter and ballast. Each of the first and second switches has a static terminal for connecting with a power supply, and four dynamic terminals for selectively connecting with the static terminal thereof. Different circuits can be configured by adjusting the connection between the static and dynamic terminals, wherein each circuit can drive a selected type of lamp tube to generate light.Type: ApplicationFiled: August 22, 2011Publication date: January 3, 2013Applicants: HON HAI PRECISION INDUSTRY CO., LTD., HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD.Inventors: QING-SHAN CAO, ZHENG-NIAN LIU, NAN ZENG, MIAO-PING GUO
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Publication number: 20120149843Abstract: The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.Type: ApplicationFiled: February 1, 2012Publication date: June 14, 2012Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Miao-Ping Chien, Nathan C. Gianneschi
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Patent number: 6599775Abstract: A method of forming an underfilled semiconductor package comprises the steps of: providing a substrate (300) with raised terminal portions (305), disposing underfill compound (5) with filler (27) on the substrate (300), placing a bumped semiconductor die (40) on the substrate (300) with bumps (45) abutting upper surfaces (310) of the raised terminal portions (305), and reflowing the assembly. During the reflow process, the raised terminal portions (305) and the bumps (45) melt and displace the filler (27) in the underfill compound (5) away from between the bumps (45) and the raised terminal portions (305). This prevents the filler (27) from forming a barrier. The molten solder forms interconnects between the pads (46) and the raised terminal portions (305).Type: GrantFiled: May 18, 2001Date of Patent: July 29, 2003Assignee: Advanpack Solutions Pte LtdInventors: Wang Tie, Miao Ping, Chew Tham Heang
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Publication number: 20020173075Abstract: A method of forming an underfilled semiconductor package comprises the steps of: providing a substrate (300) with raised terminal portions (305), disposing underfill compound (5) with filler (27) on the substrate (300), placing a bumped semiconductor die (40) on the substrate (300) with bumps (45) abutting upper surfaces (310) of the raised terminal portions (305), and reflowing the assembly. During the reflow process, the raised terminal portions (305) and the bumps (45) melt and displace the filler (27) in the underfill compound (5) away from between the bumps (45) and the raised terminal portions (305). This prevents the filler (27) from forming a barrier. The molten solder forms interconnects between the pads (46) and the raised terminal portions (305).Type: ApplicationFiled: May 18, 2001Publication date: November 21, 2002Inventors: Wang Tie, Miao Ping, Chew Tham Heang
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Patent number: D616408Type: GrantFiled: July 22, 2009Date of Patent: May 25, 2010Assignee: Hon Hai Precision Industry Co., Ltd.Inventors: Kui-Jun Wang, Miao-Ping Guo