Abstract: A method for upgrading mixed pyrolysis oil may include contacting the mixed pyrolysis oil with hydrogen in the presence of a mixed metal oxide catalyst at reaction conditions to produce a reaction effluent including light aromatic compounds. The mixed pyrolysis oil includes multi-ring aromatic compounds and is formed from light pyrolysis oil and heavy pyrolysis oil at a ratio of 10:90 to 40:60 with light pyrolysis oil representing a bottom stream of a gas steam cracker and heavy pyrolysis oil representing a bottom stream of a naphtha steam cracker. The mixed metal oxide catalyst includes a plurality of catalyst particles with each catalyst particles including a plurality of metal oxides. An associated system for upgrading mixed pyrolysis oil may include a pyrolysis upgrading unit housing the mixed metal oxide catalyst and a separation unit operable to separate used mixed metal oxide catalyst from the reaction effluent.

Abstract: The present disclosure relates to isolated anti-Ryk antibodies or antibody derivatives. In some aspects, the present disclosure relates to the use of the isolated anti-Ryk antibodies or antibody derivatives.

Abstract: A method for upgrading mixed pyrolysis oil may include contacting the mixed pyrolysis oil with hydrogen in the presence of a mixed metal oxide catalyst at reaction conditions to produce a reaction effluent including light aromatic compounds. The mixed pyrolysis oil includes multi-ring aromatic compounds and is formed from light pyrolysis oil and heavy pyrolysis oil at a ratio of 10:90 to 40:60 with light pyrolysis oil representing a bottom stream of a gas steam cracker and heavy pyrolysis oil representing a bottom stream of a naphtha steam cracker. The mixed metal oxide catalyst includes a plurality of catalyst particles with each catalyst particles including a plurality of metal oxides. An associated system for upgrading mixed pyrolysis oil may include a pyrolysis upgrading unit housing the mixed metal oxide catalyst and a separation unit operable to separate used mixed metal oxide catalyst from the reaction effluent.

Abstract: A method for producing aromatic compounds from pyrolysis oil comprises: upgrading the pyrolysis oil to pyrolysis gasoline in a multi-stage reactor comprising a slurry-phase reactor and a fixed-bed reactor, wherein the slurry-phase reactor comprises a mixed metal oxide catalyst, and the fixed-bed reactor comprises a mesoporous zeolite-supported metal catalyst; aromatizing the pyrolysis gasoline in an aromatization unit; hydrodealkylating and transalkylating a product from the aromatization unit in a hydrodealkylation-transalkylation unit, thereby producing an aromatic stream; and processing the aromatic stream in an aromatics recovery complex to produce the aromatic compounds comprising benzene, toluene, and xylenes (BTX).

Abstract: A catalytic upgrading process includes introducing a feed comprising crude oil to a steam cracking unit, thereby producing pyrolysis fuel oil (PFO). The PFO is introduced to a first catalytic depolyaromatization reactor to remove polyaromatics from the feed, thereby producing polyaromatics adsorbed to the catalyst and depolyaromatized PFO. The depolyaromatized PFO is introduced to a hydrocracking unit. The resulting benzene-toluene-xylenes (BTX) and liquid petroleum gas (LPG) are separated, and the BTX is introduced to a BTX complex to produce refined BTX. The LPG can then be introduced to the steam cracking unit. After depolyaromatization, a wash solvent is introduced into the first catalytic depolyaromatization reactor to remove the polyaromatics, regenerate the catalyst, and produce a mixture comprising the wash solvent and the polyaromatics. The wash solvent is separated from the polyaromatics.

Abstract: A method for upgrading pyrolysis oil includes contacting a pyrolysis oil feed with hydrogen in the presence of a mixed metal oxide catalyst in a first slurry reactor, where: the pyrolysis oil feed comprises multi-ring aromatic compounds comprising greater than or equal to sixteen carbon atoms, and contacting the pyrolysis oil feed with hydrogen in the presence of the mixed metal oxide catalyst in the first slurry reactor to convert at least a portion of the multi-ring aromatic compounds in the pyrolysis oil feed to light aromatic compounds comprising di-aromatic compounds, tri-aromatic compounds, or both, passing an intermediate stream comprising the light aromatic compounds to a second slurry reactor downstream of the first slurry reactor; and contacting the intermediate stream with hydrogen in the presence of a mesoporous zeolite supported metal catalyst in a second slurry reactor.

Abstract: In accordance with one or more embodiments of the present disclosure, a multi-stage process for upgrading pyrolysis oil comprising polyaromatic compounds to benzene, toluene, ethylbenzene, and xylenes (BTEX) includes upgrading the pyrolysis oil in a slurry-phase reactor zone to produce intermediate products, wherein the slurry-phase reactor zone comprises a mixed metal oxide catalyst; and hydrocracking the intermediate products in a fixed-bed reactor zone to produce the BTEX, wherein the fixed-bed reactor zone comprises a mesoporous zeolite-supported metal catalyst.

Abstract: The invention relates to a method for analysing ribonucleic acid (RNA) interactions comprising: a) cross-linking base-paired nucleotides of at least one RNA molecule and/or at least one pair of RNA molecules using a tagged, reversible cross-linking agent (preferably tagged-psoralen) under ultraviolet irradiation; b) fragmenting the said cross-linked RNA molecule(s); c) using said tag to extract said cross-linked RNA fragment(s); d) ligating the said cross-linked RNA fragment(s) to produce cross-linked ligated RNA chimera(s); e) reversing the cross-linking of the said agent to the said RNA molecule(s); f) preparing a sequence library by sequencing the ligated RNA chimera molecule(s) or pair(s); and g) analysing the sequence library to determine RNA interactions. Also disclosed is a method of studying a subject by analysing RNA interactions and attributing them to a clinical picture, or a drug discovery method by attributing an efficacy score to the drug based upon determined RNA interactions.

Abstract: A method for upgrading pyrolysis oil includes contacting a pyrolysis oil feed with hydrogen in the presence of a mixed metal oxide catalyst in a first slurry reactor, where: the pyrolysis oil feed comprises multi-ring aromatic compounds comprising greater than or equal to sixteen carbon atoms, and contacting the pyrolysis oil feed with hydrogen in the presence of the mixed metal oxide catalyst in the first slurry reactor to convert at least a portion of the multi-ring aromatic compounds in the pyrolysis oil feed to light aromatic compounds comprising di-aromatic compounds, tri-aromatic compounds, or both, passing an intermediate stream comprising the light aromatic compounds to a second slurry reactor downstream of the first slurry reactor; and contacting the intermediate stream with hydrogen in the presence of a mesoporous zeolite supported metal catalyst in a second slurry reactor.

Abstract: In accordance with one or more embodiments of the present disclosure, a multi-stage process for upgrading pyrolysis oil comprising polyaromatic compounds to benzene, toluene, ethylbenzene, and xylenes (BTEX) includes upgrading the pyrolysis oil in a slurry-phase reactor zone to produce intermediate products, wherein the slurry-phase reactor zone comprises a mixed metal oxide catalyst; and hydrocracking the intermediate products in a fixed-bed reactor zone to produce the BTEX, wherein the fixed-bed reactor zone comprises a mesoporous zeolite-supported metal catalyst.

Abstract: A catalytic upgrading process includes introducing a feed comprising crude oil to a first catalytic deasphalting reactor to deasphalt the feed, thereby producing polymerized asphaltenes and deasphalted oil (DAO). The DAO is introduced to a steam cracking unit, thereby producing pyrolysis gas (PG), which is introduced into a selective hydrogenation unit, thereby producing an olefin-free product, which can then be introduced to a separation unit. The resulting benzene-toluene-xylenes (BTX)-containing stream and liquid petroleum gas (LPG) are separated, and the BTX-containing stream is introduced to a BTX complex to produce refined BTX. After deasphalting, a wash solvent may be introduced into the first catalytic deasphalting reactor to remove the polymerized asphaltenes, regenerate the catalyst, and produce a mixture comprising the wash solvent and the polymerized asphaltenes. The wash solvent is separated from the polymerized asphaltenes.

Abstract: The present disclosure relates to a field programmable gate array (FPGA)-based multi-channel dynamic light scattering (DLS) autocorrelation system and method. The system includes a DLS generation apparatus, a photon correlator, and a host computer, where the photon correlator includes an FPGA and a universal serial bus (USB) communication module; the DLS generation apparatus is connected to the FPGA; the FPGA is configured to count and perform correlation calculation on photon pulses generated by the DLS generation apparatus; the USB communication module is connected to the host computer; the FPGA includes a dual counter module and a correlation calculation module; the dual counter module is connected to the DLS generation apparatus and the correlation calculation module; the correlation calculation module is connected to the USB communication module; the dual counter module includes a plurality of dual counters; and the correlation calculation module includes a plurality of correlators.

Abstract: A method for upgrading pyrolysis oil includes contacting a pyrolysis oil feed with hydrogen in the presence of a mixed metal oxide catalyst in a first slurry reactor, where: the pyrolysis oil feed comprises multi-ring aromatic compounds comprising greater than or equal to sixteen carbon atoms, and contacting the pyrolysis oil feed with hydrogen in the presence of the mixed metal oxide catalyst in the first slurry reactor to convert at least a portion of the multi-ring aromatic compounds in the pyrolysis oil feed to light aromatic compounds comprising di-aromatic compounds, tri-aromatic compounds, or both, passing an intermediate stream comprising the light aromatic compounds to a second slurry reactor downstream of the first slurry reactor; and contacting the intermediate stream with hydrogen in the presence of a mesoporous zeolite supported metal catalyst in a second slurry reactor.

Abstract: A catalytic upgrading process includes introducing a feed comprising crude oil to a first catalytic deasphalting reactor to deasphalt the feed, thereby producing polymerized asphaltenes and deasphalted oil (DAO). The DAO is introduced to a steam cracking unit, thereby producing pyrolysis gas (PG), which is introduced into a selective hydrogenation unit, thereby producing an olefin-free product, which can then be introduced to a separation unit. The resulting benzene-toluene-xylenes (BTX)-containing stream and liquid petroleum gas (LPG) are separated, and the BTX-containing stream is introduced to a BTX complex to produce refined BTX. After deasphalting, a wash solvent may be introduced into the first catalytic deasphalting reactor to remove the polymerized asphaltenes, regenerate the catalyst, and produce a mixture comprising the wash solvent and the polymerized asphaltenes. The wash solvent is separated from the polymerized asphaltenes.

Abstract: A catalytic upgrading process includes introducing a feed comprising crude oil to a steam cracking unit, thereby producing pyrolysis fuel oil (PFO). The PFO is introduced to a first catalytic depolyaromatization reactor to remove polyaromatics from the feed, thereby producing polyaromatics adsorbed to the catalyst and depolyaromatized PFO. The depolyaromatized PFO is introduced to a hydrocracking unit. The resulting benzene-toluene-xylenes (BTX) and liquid petroleum gas (LPG) are separated, and the BTX is introduced to a BTX complex to produce refined BTX. The LPG can then be introduced to the steam cracking unit. After depolyaromatization, a wash solvent is introduced into the first catalytic depolyaromatization reactor to remove the polyaromatics, regenerate the catalyst, and produce a mixture comprising the wash solvent and the polyaromatics. The wash solvent is separated from the polyaromatics.

Abstract: A system for upgrading pyrolysis oil may include a pyrolysis upgrading unit having a mixed metal oxide catalyst and a separation unit operable to separate used mixed metal oxide catalyst from a reaction effluent. A method for upgrading pyrolysis oil may include contacting the pyrolysis oil with hydrogen in the presence of the mixed metal oxide catalyst at reaction conditions to produce a reaction effluent. The pyrolysis oil may include multi-ring aromatic compounds. The mixed metal oxide catalyst may include a plurality of catalyst particles and each of the plurality of catalyst particles having a plurality of metal oxides. Contacting the pyrolysis oil with hydrogen in the presence of the mixed metal oxide catalyst at the reaction conditions may convert at least a portion of the multi-ring aromatic compounds in the pyrolysis oil to the light aromatic compounds.

Abstract: A system for upgrading pyrolysis oil may include a pyrolysis upgrading unit having a mixed metal oxide catalyst and a separation unit operable to separate used mixed metal oxide catalyst from a reaction effluent. A method for upgrading pyrolysis oil may include contacting the pyrolysis oil with hydrogen in the presence of the mixed metal oxide catalyst at reaction conditions to produce a reaction effluent. The pyrolysis oil may include multi-ring aromatic compounds. The mixed metal oxide catalyst may include a plurality of catalyst particles and each of the plurality of catalyst particles having a plurality of metal oxides. Contacting the pyrolysis oil with hydrogen in the presence of the mixed metal oxide catalyst at the reaction conditions may convert at least a portion of the multi-ring aromatic compounds in the pyrolysis oil to the light aromatic compounds.

Abstract: A method for upgrading pyrolysis oil includes contacting a pyrolysis oil feed with hydrogen in the presence of a mixed metal oxide catalyst in a slurry reactor to produce an intermediate stream comprising light aromatic compounds comprising mono-aromatic compounds, di-aromatic compounds, or both, passing the intermediate stream to a hydrocracking reactor, contacting the intermediate stream with hydrogen in the presence of a hydrocracking catalyst in a hydrocracking reactor to produce a hydrocracking effluent comprising aromatic compounds having six to nine carbon atoms, passing the hydrocracking effluent to a transalkylation reactor, and contacting the hydrocracking effluent with hydrogen in the presence of a transalkylation catalyst in the transalkylation reactor to produce a transalkylation effluent comprising xylenes.

Abstract: Systems and methods communicate an intent of an autonomous vehicle externally. In one implementation, scan data of a field around a travel path of an autonomous vehicle is obtained. The scan data is captured using at least one sensor. An object in the field around the travel path is determined from the scan data. The object is determined to be mutable or immutable. A navigation condition associated with the object is determined based on whether the object is mutable or immutable. The navigation condition is correlated to a portion of the travel path. Control operation(s) of the autonomous vehicle is determined for the portion of the travel path in response to the navigation condition. A representation link between the control operation(s) of the autonomous vehicle and the object is generated. A representation of the field around the travel path is rendered and includes the representation link.