Patents by Inventor Miaoge XUE

Miaoge XUE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated rotavirus VP4 protein and application thereof
    Patent number: 11339194
    Abstract: The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: May 24, 2022
    Assignees: Xiamen University, Xiamen Innovax Biotech Co., Ltd.
    Inventors: Shengxiang Ge, Tingdong Li, Lianzhi Jia, Yijian Li, Miaoge Xue, Yuanjun Zeng, Huirong Pan, Jun Zhang, Ningshao Xia
  • METHODS AND COMPOSITIONS FOR TREATING NEGATIVE-SENSE SINGLE-STRANDED RNA VIRUS
    Publication number: 20220033783
    Abstract: The current disclosure relates to methods, compositions and kits for detecting modified adenosine in a target RNA molecule. Aspects relate to a method for detecting modified adenosine in a target ribonucleic acid (RNA) comprising contacting the target RNA with an adenosine deaminase enzyme (adenosine deaminase, RNA-specific) to generate a target RNA with deaminated adenosines and sequencing the target RNA with deaminated adenosines; wherein the modified adenosine is detected when the nucleotide sequence includes adenosine within a m6A motif.
    Type: Application
    Filed: October 18, 2019
    Publication date: February 3, 2022
    Applicants: The University of Chicago, Nationwide Children's Hospital, The Ohio State University
    Inventors: Jianrong LI, Mark E. PEEPLES, Chuan HE, Stefan NIEWIESK, Mijia LU, Miaoge XUE, Zijie ZHANG, Boxuan ZHAO
  • TRUNCATED ROTAVIRUS VP4 PROTEIN AND APPLICATION THEREOF
    Publication number: 20200308233
    Abstract: The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
    Type: Application
    Filed: June 15, 2020
    Publication date: October 1, 2020
    Inventors: Shengxiang Ge, Tingdong Li, Lianzhi Jia, Yijian Li, Miaoge Xue, Yuanjun Zeng, Huirong Pan, Jun Zhang, Ningshao Xia
  • Truncated rotavirus VP4 protein and application thereof
    Patent number: 10723767
    Abstract: The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: July 28, 2020
    Assignees: Xiamen University, Xiamen Innovax Biotech Co., Ltd.
    Inventors: Shengxiang Ge, Tingdong Li, Lianzhi Jia, Yijian Li, Miaoge Xue, Yuanjun Zeng, Huirong Pan, Jun Zhang, Ningshao Xia
  • Truncated Rotavirus VP4 Protein And Application Thereof
    Publication number: 20180141978
    Abstract: The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
    Type: Application
    Filed: May 20, 2016
    Publication date: May 24, 2018
    Inventors: Shengxiang GE, Tingdong LI, Lianzhi JIA, Yijian LI, Miaoge XUE, Yuanjun ZENG, Jun ZHANG, Ningshao XIA